KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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1 Online-Ressource.
- Language
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Englisch
- Bibliographic citation
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KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma ; volume:15 ; number:1 ; day:24 ; month:2 ; year:2024 ; pages:1-19 ; date:12.2024
Nature Communications ; 15, Heft 1 (24.2.2024), 1-19, 12.2024
- Creator
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Kim, Yong Yean
Gryder, Berkley E.
Sinniah, Ranuka
Peach, Megan L.
Shern, Jack F.
Abdelmaksoud, Abdalla
Pomella, Silvia
Woldemichael, Girma M.
Stanton, Benjamin Z.
Milewski, David
Barchi, Joseph J.
Schneekloth, John S.
Chari, Raj
Kowalczyk, Joshua T.
Shenoy, Shilpa R.
Evans, Jason R.
Song, Young K.
Wang, Chaoyu
Wen, Xinyu
Chou, Hsien-Chao
Gangalapudi, Vineela
Esposito, Dominic
Jones, Jane
Procter, Lauren
O’Neill, Maura
Jenkins, Lisa M.
Tarasova, Nadya I.
Wei, Jun S.
McMahon, James B.
O’Keefe, Barry R.
Hawley, Robert
Khan, Javed
- Contributor
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SpringerLink (Online service)
- DOI
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10.1038/s41467-024-45902-y
- URN
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urn:nbn:de:101:1-2405020851318.929502607082
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
14.08.2025, 11:01 AM CEST
Data provider
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Associated
- Kim, Yong Yean
- Gryder, Berkley E.
- Sinniah, Ranuka
- Peach, Megan L.
- Shern, Jack F.
- Abdelmaksoud, Abdalla
- Pomella, Silvia
- Woldemichael, Girma M.
- Stanton, Benjamin Z.
- Milewski, David
- Barchi, Joseph J.
- Schneekloth, John S.
- Chari, Raj
- Kowalczyk, Joshua T.
- Shenoy, Shilpa R.
- Evans, Jason R.
- Song, Young K.
- Wang, Chaoyu
- Wen, Xinyu
- Chou, Hsien-Chao
- Gangalapudi, Vineela
- Esposito, Dominic
- Jones, Jane
- Procter, Lauren
- O’Neill, Maura
- Jenkins, Lisa M.
- Tarasova, Nadya I.
- Wei, Jun S.
- McMahon, James B.
- O’Keefe, Barry R.
- Hawley, Robert
- Khan, Javed
- SpringerLink (Online service)
Other Objects (12)
Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
Regulatory landscape fusion in rhabdomyosarcoma through interactions between the PAX3 promoter and FOXO1 regulatory elements
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma
Analysis of oncogenic RAS and ALK signaling networks in rhabdomyosarcoma
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma
TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma
PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma
Self-assembled DNA nanostructure containing oncogenic miRNA-mediated cell proliferation by downregulation of FOXO1 expression
The oncogenic fusion landscape in pediatric CNS neoplasms
FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas
ACTA1 is inhibited by PAX3-FOXO1 through RhoA-MKL1-SRF signaling pathway and impairs cell proliferation, migration and tumor growth in Alveolar Rhabdomyosarcoma
Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
Regulatory landscape fusion in rhabdomyosarcoma through interactions between the PAX3 promoter and FOXO1 regulatory elements
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma
Analysis of oncogenic RAS and ALK signaling networks in rhabdomyosarcoma
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma
TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma
PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma
Self-assembled DNA nanostructure containing oncogenic miRNA-mediated cell proliferation by downregulation of FOXO1 expression
The oncogenic fusion landscape in pediatric CNS neoplasms
FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas
ACTA1 is inhibited by PAX3-FOXO1 through RhoA-MKL1-SRF signaling pathway and impairs cell proliferation, migration and tumor growth in Alveolar Rhabdomyosarcoma
Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
Regulatory landscape fusion in rhabdomyosarcoma through interactions between the PAX3 promoter and FOXO1 regulatory elements
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma
Analysis of oncogenic RAS and ALK signaling networks in rhabdomyosarcoma
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma
TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma
PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma
Self-assembled DNA nanostructure containing oncogenic miRNA-mediated cell proliferation by downregulation of FOXO1 expression
The oncogenic fusion landscape in pediatric CNS neoplasms
FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas