Arbeitspapier

A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay

To estimate the effective dose level ED a in the common binary response model, several parametric and nonparametric estimators have been proposed in the literature. In the present paper, we focus on nonparametric methods and present a detailed numerical comparison of four different approaches to estimate the ED a nonparametrically. The methods are briefly reviewed and their finite sample properties are studied by means of a detailed simulation study. Moreover, a data example is presented to illustrate the different concepts.

Language
Englisch

Bibliographic citation
Series: Technical Report ; No. 2008,05

Subject
Binary response model
effective dose level
nonparametric regression
isotonic regression
order restricted inference
local linear regression

Event
Geistige Schöpfung
(who)
Dette, Holger
Scheder, Regine
Event
Veröffentlichung
(who)
Technische Universität Dortmund, Sonderforschungsbereich 475 - Komplexitätsreduktion in Multivariaten Datenstrukturen
(where)
Dortmund
(when)
2008

Handle
Last update
10.03.2025, 11:44 AM CET

Data provider

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Object type

  • Arbeitspapier

Associated

  • Dette, Holger
  • Scheder, Regine
  • Technische Universität Dortmund, Sonderforschungsbereich 475 - Komplexitätsreduktion in Multivariaten Datenstrukturen

Time of origin

  • 2008

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