Arbeitspapier
A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay
To estimate the effective dose level ED a in the common binary response model, several parametric and nonparametric estimators have been proposed in the literature. In the present paper, we focus on nonparametric methods and present a detailed numerical comparison of four different approaches to estimate the ED a nonparametrically. The methods are briefly reviewed and their finite sample properties are studied by means of a detailed simulation study. Moreover, a data example is presented to illustrate the different concepts.
- Language
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Englisch
- Bibliographic citation
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Series: Technical Report ; No. 2008,05
- Subject
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Binary response model
effective dose level
nonparametric regression
isotonic regression
order restricted inference
local linear regression
- Event
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Geistige Schöpfung
- (who)
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Dette, Holger
Scheder, Regine
- Event
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Veröffentlichung
- (who)
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Technische Universität Dortmund, Sonderforschungsbereich 475 - Komplexitätsreduktion in Multivariaten Datenstrukturen
- (where)
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Dortmund
- (when)
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2008
- Handle
- Last update
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10.03.2025, 11:44 AM CET
Data provider
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Object type
- Arbeitspapier
Associated
- Dette, Holger
- Scheder, Regine
- Technische Universität Dortmund, Sonderforschungsbereich 475 - Komplexitätsreduktion in Multivariaten Datenstrukturen
Time of origin
- 2008