Dosimetric Considerations in Radioimmunotherapy and Systemic Radionuclide Therapies: A Review

Radiopharmaceutical therapy, once touted as the "magic bullet" in radiation oncology, is increasingly being used in the treatment of a variety of malignancies; albeit in later disease stages. With ever-increasing public and medical awareness of radiation effects, radiation dosimetry is becoming more important. Dosimetry allows administration of the maximum tolerated radiation dose to the tumor/organ to be treated but limiting radiation to critical organs. Traditional tumor dosimetry involved acquiring pretherapy planar scans and plasma estimates with a diagnostic dose of intended radiopharmaceuticals. New advancements in single photon emission computed tomography and positron emission tomography systems allow semi-quantitative measurements of radiation dosimetry thus allowing treatments tailored to each individual patient.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Dosimetric Considerations in Radioimmunotherapy and Systemic Radionuclide Therapies: A Review ; volume:10 ; number:02 ; year:2011 ; pages:122-138
World Journal of Nuclear Medicine ; 10, Heft 02 (2011), 122-138

Contributor
Loke, Kelvin
Padhy, Ajit
Ng, David
Goh, Anthony
Divgi, Chaitanya

DOI
10.4103/1450-1147.89780
URN
urn:nbn:de:101:1-2022071410323836892651
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.20252025, 3:31 AM CEST

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Associated

  • Loke, Kelvin
  • Padhy, Ajit
  • Ng, David
  • Goh, Anthony
  • Divgi, Chaitanya

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