Association between hair cortisol concentration and metabolic syndrome
Abstract: Metabolic syndrome (MetS) is a highly prevalent disorder defined as a cluster of cardiometabolic risk factors including obesity, hyperglycemia, hypertension, and dyslipidemia. It is believed that excessive cortisol secretion due to psychosocial stress-induced hypothalamic-pituitary-adrenal axis activation might be involved in the pathogenesis of MetS. We sought to explore the association between MetS and psychosocial risk factors, as well as cortisol concentration measured in different biological specimens including saliva, blood serum, and hair samples. The study was conducted on a sample of 163 young and middle-aged men who were divided into groups according to the presence of MetS. Hair cortisol concentration (HCC) was determined using high performance liquid chromatography with UV detection, while blood serum and salivary cortisol levels were measured by enzyme-linked immunoassay. Lipid metabolism biomarkers were determined using routine laboratory methods. Anthropometric and lifestyle characteristics, as well as self-reported psychosocial indicators, were also examined. Significantly higher HCC and lower social support level among participants with MetS compared with individuals without MetS were found. However, no significant differences in blood serum and salivary cortisol levels were observed between men with and without MetS. In conclusion, chronically elevated cortisol concentration might be a potential contributing factor to the development of MetS.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Association between hair cortisol concentration and metabolic syndrome ; volume:16 ; number:1 ; year:2021 ; pages:873-881 ; extent:9
Open medicine ; 16, Heft 1 (2021), 873-881 (gesamt 9)
- Creator
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Mazgelytė, Eglė
Mažeikienė, Asta
Burokienė, Neringa
Matuzevičienė, Rėda
Linkevičiūtė, Aušra
Kučinskienė, Zita Aušrelė
Karčiauskaitė, Dovilė
- DOI
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10.1515/med-2021-0298
- URN
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urn:nbn:de:101:1-2022092014402634253026
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:22 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Mazgelytė, Eglė
- Mažeikienė, Asta
- Burokienė, Neringa
- Matuzevičienė, Rėda
- Linkevičiūtė, Aušra
- Kučinskienė, Zita Aušrelė
- Karčiauskaitė, Dovilė
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Correction to: Prospective associations between burnout symptomatology and hair cortisol
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Hair cortisol concentration in Siberian flying squirrels is unrelated to landscape and social factors
Predicting Hair Cortisol and Cortisone Concentration in Postpartum Women through Repeated Measurements of Perceived Stress
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