Effectiveness of nutritional support for clinical outcomes in gastric cancer patients: A meta-analysis of randomized controlled trials
Background: Gastric cancer (GC) is a leading cause of cancer-related morbidity and mortality globally. This meta-analysis was conducted to assess the impact of nutritional interventions on clinical outcomes in GC patients. Methods: Comprehensive search was conducted across four medical databases to identify randomized controlled trials (RCTs) that examined nutritional interventions in GC patients. The outcomes assessed included hospitalization duration, nutritional status, immune function, and complications. Results: A total of 11 studies were included. Enteral nutrition (EN) significantly reduce hospital stay duration compared to no nutritional intervention (SMD = −1.22, 95% CI [−1.72, −0.73], P < 0.001) and parenteral nutrition (PN) (SMD = −1.30, 95% CI [−1.78, −0.82], P < 0.001), but showed no significant difference compared to immunonutrition (IN). EN also improved nutritional status, indicated by higher albumin prealbumin levels, and improved immune function by elevating CD4+ levels (SMD = 1.09, 95% CI [0.61, 1.57], P < 0.001). However, IN showed superior effects on immunoglobulin levels (IgG and IgM). No significant differences were observed in complication rates among EN, IN, and PN interventions. Conclusion: Nutritional support, particularly EN and IN, can significantly improve hospitalization outcomes, nutritional status, and immune function. Customizing interventions according to patient requirements can optimize therapeutic outcomes, highlighting the need for further research in this area.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Effectiveness of nutritional support for clinical outcomes in gastric cancer patients: A meta-analysis of randomized controlled trials ; volume:19 ; number:1 ; year:2024 ; extent:13
Open medicine ; 19, Heft 1 (2024) (gesamt 13)
- Urheber
-
Zhang, Juping
Kong, Qian
Zhang, Jibo
Guo, Jun
- DOI
-
10.1515/med-2024-1023
- URN
-
urn:nbn:de:101:1-2409071708451.122516686564
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:24 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Zhang, Juping
- Kong, Qian
- Zhang, Jibo
- Guo, Jun
Ähnliche Objekte (12)
Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor
A dimension expanded preconditioning technique for block two-by-two linear equations
A comparison of two nonconforming finite element methods for linear three-field poroelasticity
Characteristics of ventilator-associated pneumonia due to hypervirulent Klebsiella pneumoniae genotype in genetic background for the elderly in two tertiary hospitals in China
Stating Rules or Imparting Knowledge? An Intervention Experiment on the Trust and Sharing of Seismic Rumors in the Beijing-Tianjin-Hebei Area of China
Metal–Organic Framework-Based Solid Acid Materials for Biomass Upgrade
De novo biosynthesis of antiarrhythmic alkaloid ajmaline
Salient context-based semantic matching for information retrieval
The association between combustible/electronic cigarette use and stroke based on national health and nutrition examination survey
The analysis of the lipid levels in patients with coronary artery disease after percutaneous coronary intervention: a one-year follow-up observational study
Asymmetric remote C-H borylation of internal alkenes via alkene isomerization
Trauma-induced complete pacemaker lead fracture 8 months prior to hospitalization: A case report
Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor
A dimension expanded preconditioning technique for block two-by-two linear equations
A comparison of two nonconforming finite element methods for linear three-field poroelasticity
Characteristics of ventilator-associated pneumonia due to hypervirulent Klebsiella pneumoniae genotype in genetic background for the elderly in two tertiary hospitals in China
Stating Rules or Imparting Knowledge? An Intervention Experiment on the Trust and Sharing of Seismic Rumors in the Beijing-Tianjin-Hebei Area of China
Metal–Organic Framework-Based Solid Acid Materials for Biomass Upgrade
De novo biosynthesis of antiarrhythmic alkaloid ajmaline
Salient context-based semantic matching for information retrieval
The association between combustible/electronic cigarette use and stroke based on national health and nutrition examination survey
The analysis of the lipid levels in patients with coronary artery disease after percutaneous coronary intervention: a one-year follow-up observational study
Asymmetric remote C-H borylation of internal alkenes via alkene isomerization
Trauma-induced complete pacemaker lead fracture 8 months prior to hospitalization: A case report
Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor
A dimension expanded preconditioning technique for block two-by-two linear equations
A comparison of two nonconforming finite element methods for linear three-field poroelasticity
Characteristics of ventilator-associated pneumonia due to hypervirulent Klebsiella pneumoniae genotype in genetic background for the elderly in two tertiary hospitals in China
Stating Rules or Imparting Knowledge? An Intervention Experiment on the Trust and Sharing of Seismic Rumors in the Beijing-Tianjin-Hebei Area of China
Metal–Organic Framework-Based Solid Acid Materials for Biomass Upgrade
De novo biosynthesis of antiarrhythmic alkaloid ajmaline
Salient context-based semantic matching for information retrieval
The association between combustible/electronic cigarette use and stroke based on national health and nutrition examination survey
The analysis of the lipid levels in patients with coronary artery disease after percutaneous coronary intervention: a one-year follow-up observational study
Asymmetric remote C-H borylation of internal alkenes via alkene isomerization