C−H Activation Based Functionalization of Furfural Derivatives
Abstract: Furfural and related compounds are building blocks of industrial interest, obtained from raw biomass. Their use as precursors of basic and fine chemicals has gained increasing attention as a green alternative to petroleum‐derived compounds. Several works have reported the functionalization of furfurals to obtain a wider range of chemicals, opening up new synthetic possibilities and applications, ranging from biofuels to pharmaceuticals. Among these works, processes based on C−H activation are the most attractive ones for their atom economy and the possibility to use non‐activated substrates. This minireview summarizes the reported methods of direct C−H functionalization of furfurals without prior modification of the redox state of the aldehyde function. In particular, the transition metal catalyzed functionalization of each bond of the heteroaromatic nucleus of these molecules is systematically discussed, as well as examples of C−H transformations of the aldehyde function.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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C−H Activation Based Functionalization of Furfural Derivatives ; day:25 ; month:08 ; year:2022 ; extent:1
European journal of organic chemistry ; (25.08.2022) (gesamt 1)
- Creator
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Mori, Alessia
Curpanen, Sebastien
Pezzetta, Cristofer
Perez-Luna, Alejandro
Poli, Giovanni
Oble, Julie
- DOI
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10.1002/ejoc.202200727
- URN
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urn:nbn:de:101:1-2022082916000824115299
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:30 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Mori, Alessia
- Curpanen, Sebastien
- Pezzetta, Cristofer
- Perez-Luna, Alejandro
- Poli, Giovanni
- Oble, Julie
Other Objects (12)
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Selective synthesis of 1,5-pentanediol from furfural derivatives over stable nickel-based catalysts
Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
Domino C-H functionalization/cascade catalysis
Hydroxymethylfurfural und Furfural in Röstgetränken
P(O)R2-directed Pd-catalyzed C–H functionalization of biaryl derivatives to synthesize chiral phosphorous ligands
Palladium-catalyzed dual C–H or N–H functionalization of unfunctionalized indole derivatives with alkenes and arenes
Synthesis and functionalization of optically active C-Allylglycine derivatives
Special topic C-H functionalization, activation
C–H Functionalization/activation in organic synthesis
Resource-Economical C–H Activation for Late-Stage Functionalization
C3-Alkylation of furfural derivatives by continuous flow homogeneous catalysis
C–H Functionalization
Selective synthesis of 1,5-pentanediol from furfural derivatives over stable nickel-based catalysts
Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
Domino C-H functionalization/cascade catalysis
Hydroxymethylfurfural und Furfural in Röstgetränken
P(O)R2-directed Pd-catalyzed C–H functionalization of biaryl derivatives to synthesize chiral phosphorous ligands
Palladium-catalyzed dual C–H or N–H functionalization of unfunctionalized indole derivatives with alkenes and arenes
Synthesis and functionalization of optically active C-Allylglycine derivatives
Special topic C-H functionalization, activation
C–H Functionalization/activation in organic synthesis
Resource-Economical C–H Activation for Late-Stage Functionalization
C3-Alkylation of furfural derivatives by continuous flow homogeneous catalysis
C–H Functionalization
Selective synthesis of 1,5-pentanediol from furfural derivatives over stable nickel-based catalysts
Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
Domino C-H functionalization/cascade catalysis
Hydroxymethylfurfural und Furfural in Röstgetränken
P(O)R2-directed Pd-catalyzed C–H functionalization of biaryl derivatives to synthesize chiral phosphorous ligands
Palladium-catalyzed dual C–H or N–H functionalization of unfunctionalized indole derivatives with alkenes and arenes