Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

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Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: In: Acta Neuropathologica Communications (2020) 8:116 https://doi.org/10.1186/s40478-020-00987-6

Event: Veröffentlichung

(where): Würzburg

(who): Universität Würzburg

(when): 2021

Creator: Briese, Michael
Saal-Bauernschubert, Lena
Lüningschrör, Patrick
Moradi, Mehri
Dombert, Benjamin
Surrey, Verena
Appenzeller, Silke
Deng, Chunchu
Jablonka, Sibylle
Sendtner, Michael

DOI: 10.1186/s40478-020-00987-6

URN: urn:nbn:de:bvb:20-opus-230322

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:48 AM CEST

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Associated

Briese, Michael
Saal-Bauernschubert, Lena
Lüningschrör, Patrick
Moradi, Mehri
Dombert, Benjamin
Surrey, Verena
Appenzeller, Silke
Deng, Chunchu
Jablonka, Sibylle
Sendtner, Michael
Universität Würzburg

Time of origin

2021

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Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

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Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

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Whole transcriptome profiling of compartmentalized motoneurons

Axonal hnRNP R: regulation by Ptbp2 and functions in neurodegenerative disorders

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Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

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Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications.

Towards a comprehensive understanding of the trophic support of motoneurons

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Differential roles of α-, β- and γ-actin isoforms in regulation of cytoskeletal dynamics and stability during axon elongation and collateral branch formation in motoneurons

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

Members of several gene families influence survival of rat motoneurons in vitro and in vivo

Neurotrophic factors and their action on motoneuron survival: Implications for neuromuscular disorders

Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

Hochschulschrift

Whole transcriptome profiling of compartmentalized motoneurons

Axonal hnRNP R: regulation by Ptbp2 and functions in neurodegenerative disorders

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Role of NaV1.9 in activity dependent axon growth in embryonic cultured motoneurons

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Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to Chromatin

Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications.

Towards a comprehensive understanding of the trophic support of motoneurons

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Differential roles of α-, β- and γ-actin isoforms in regulation of cytoskeletal dynamics and stability during axon elongation and collateral branch formation in motoneurons

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

Members of several gene families influence survival of rat motoneurons in vitro and in vivo

Neurotrophic factors and their action on motoneuron survival: Implications for neuromuscular disorders

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Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

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Other Objects (12)

Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

Whole transcriptome profiling of compartmentalized motoneurons

Axonal hnRNP R: regulation by Ptbp2 and functions in neurodegenerative disorders

Role of NaV1.9 in activity dependent axon growth in embryonic cultured motoneurons

Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to Chromatin

Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications.

Towards a comprehensive understanding of the trophic support of motoneurons

Differential roles of α-, β- and γ-actin isoforms in regulation of cytoskeletal dynamics and stability during axon elongation and collateral branch formation in motoneurons

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

Members of several gene families influence survival of rat motoneurons in vitro and in vivo

Neurotrophic factors and their action on motoneuron survival: Implications for neuromuscular disorders

Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

Whole transcriptome profiling of compartmentalized motoneurons

Axonal hnRNP R: regulation by Ptbp2 and functions in neurodegenerative disorders

Role of NaV1.9 in activity dependent axon growth in embryonic cultured motoneurons

Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to Chromatin

Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications.

Towards a comprehensive understanding of the trophic support of motoneurons

Differential roles of α-, β- and γ-actin isoforms in regulation of cytoskeletal dynamics and stability during axon elongation and collateral branch formation in motoneurons

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

Members of several gene families influence survival of rat motoneurons in vitro and in vivo

Neurotrophic factors and their action on motoneuron survival: Implications for neuromuscular disorders

Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function

Whole transcriptome profiling of compartmentalized motoneurons

Axonal hnRNP R: regulation by Ptbp2 and functions in neurodegenerative disorders

Role of NaV1.9 in activity dependent axon growth in embryonic cultured motoneurons

Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to Chromatin

Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications.

Towards a comprehensive understanding of the trophic support of motoneurons

Differential roles of α-, β- and γ-actin isoforms in regulation of cytoskeletal dynamics and stability during axon elongation and collateral branch formation in motoneurons

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

Members of several gene families influence survival of rat motoneurons in vitro and in vivo

Neurotrophic factors and their action on motoneuron survival: Implications for neuromuscular disorders

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