Gold Trifluoromethyl Complexes as Efficient Regioselective Catalysts in Alkyne Hydration

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Abstract: Gold (III) complexes containing trifluoromethyl ligands are efficient catalysts in the hydration of alkynes, operating at low catalyst loadings, without additives, using environmentally friendly solvents and at mild conditions (60 °C). Hydration of terminal and internal alkynes provides the corresponding ketones in quantitative yields without special precautions as dry solvents or inert atmospheres. Remarkably, hydration of asymmetric internal alkynes proceeds with moderate to notable regioselectivities, providing mixtures of the two possible isomers with ratios up to 90: 10.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Gold Trifluoromethyl Complexes as Efficient Regioselective Catalysts in Alkyne Hydration ; volume:30 ; number:52 ; year:2024 ; extent:6
Chemistry - a European journal ; 30, Heft 52 (2024) (gesamt 6)

Creator
Ruiz‐Almoguera, David
Ventura‐Espinosa, David
Pérez-Bitrián, Alberto
Martín, Antonio
Mata, José A.
Baya, Miguel

DOI
10.1002/chem.202401753
URN
urn:nbn:de:101:1-2410011420374.677639724127
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:34 AM CEST

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Associated

  • Ruiz‐Almoguera, David
  • Ventura‐Espinosa, David
  • Pérez-Bitrián, Alberto
  • Martín, Antonio
  • Mata, José A.
  • Baya, Miguel

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