Lipid Nanoparticle (LNP) ‐A Vector Suitable for Evolving Therapies for Advanced Hepatocellular Carcinoma (HCC)

Abstract: Hepatocellular carcinoma (HCC) stands as the predominant form of primary liver cancer, characterized by a dismal prognosis. Therapeutic options for advanced HCC remain sparse, with efficacy significantly hampered by the emergence of drug resistance. In parallel with research into novel pharmacological agents, advances in drug delivery systems represent a promising avenue for overcoming resistance. Lipid nanoparticles (LNPs) have demonstrated considerable efficacy in the delivery of nucleic acid‐based therapeutics and hold potential for broader applications in drug delivery. This review describes the development of LNPs tailored for HCC treatment and consolidates recent investigations using LNPs to target HCC.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Lipid Nanoparticle (LNP) ‐A Vector Suitable for Evolving Therapies for Advanced Hepatocellular Carcinoma (HCC) ; day:25 ; month:11 ; year:2024 ; extent:10
Global challenges ; (25.11.2024) (gesamt 10)

Urheber
Zhang, Mingxuan
Guo, Ruiping
Yuan, Zhuhui
Wang, Hao

DOI
10.1002/gch2.202400217
URN
urn:nbn:de:101:1-2411261335536.732094515429
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.11.2025, 07:19 MEZ

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Beteiligte

  • Zhang, Mingxuan
  • Guo, Ruiping
  • Yuan, Zhuhui
  • Wang, Hao

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