Hodgkin Lymphoma on Hemodialysis Successfully Treated with Extended Courses of Brentuximab Vedotin

Chemotherapy for hemodialysis (HD) patients is a challenging situation because HD patients are generally frail, and the pharmacokinetics and pharmacodynamics of most chemotherapeutics in HD patients are unknown. We report a classical Hodgkin lymphoma (cHL) patient successfully treated with 34 courses of brentuximab vedotin (BV) monotherapy, of which 30 courses were carried out during HD. Although grade 2 peripheral sensory neuropathy and one occasion of febrile neutropenia were observed, treatment was well-tolerated overall and effective. This is the first report of successful BV administration in a cHL patient on HD, and also the first to report efficacy and safety of extended courses of BV in an HD patient. Treatment options for cHL in the HD patient are limited, and extended courses of BV monotherapy may be an optimal treatment approach for some patients.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Hodgkin Lymphoma on Hemodialysis Successfully Treated with Extended Courses of Brentuximab Vedotin ; volume:15 ; number:1 ; year:2022 ; pages:263-266 ; extent:4 ; Case reports in oncology ; 15, Heft 1 (2022), 263-266 (gesamt 4)

Beteiligte, Orts- und Zeitangaben

• Urheber: Uchimura, Ayana ; Yasuda, Hajime ; Ando, Jun ; Ota, Yasunori ; Sasaki, Makoto ; Takaku, Tomoiku ; Tsukune, Yutaka ; Tsutsui, Miyuki ; Edahiro, Yoko ; Watanabe, Naoki ; Ochiai, Tomonori ; Komatsu, Norio ; Ando, Miki

Weitere Informationen

• DOI: 10.1159/000523823
• URN: urn:nbn:de:101:1-2022051201043680458683
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 15.08.2025, 07:29 MESZ