CRISPR/Cas9-induced double-strand breaks in the huntingtin locus lead to CAG repeat contraction through DNA end resection and homology-mediated repair
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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1 Online-Ressource.
- Language
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Englisch
- Bibliographic citation
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CRISPR/Cas9-induced double-strand breaks in the huntingtin locus lead to CAG repeat contraction through DNA end resection and homology-mediated repair ; volume:22 ; number:1 ; day:3 ; month:12 ; year:2024 ; pages:1-21 ; date:12.2024
BMC biology ; 22, Heft 1 (3.12.2024), 1-21, 12.2024
- Creator
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Sledzinski, Pawel
Nowaczyk, Mateusz
Smielowska, Marianna Iga
Olejniczak, Marta
- Contributor
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SpringerLink (Online service)
- DOI
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10.1186/s12915-024-02079-6
- URN
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urn:nbn:de:101:1-2502172208218.402740995501
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:37 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Sledzinski, Pawel
- Nowaczyk, Mateusz
- Smielowska, Marianna Iga
- Olejniczak, Marta
- SpringerLink (Online service)
Other Objects (12)
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Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Correction: Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Reducing mutant Huntingtin protein expression in living cells by a newly identified RNA CAG binder
Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum
Characterization of the CagT4SS proteins CagN and CagM
Huntingtin assoziierte Proteine
Huntingtin Lowering Strategies
Julius, C.A.G.
Huntingtin CAG repeat size variations below the Huntington’s disease threshold: associations with depression, anxiety and basal ganglia structure
Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome
Monitoring homology search during DNA double-strand break repair in vivo
Monitoring homology search during DNA double-strand break repair in vivo
Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Correction: Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Reducing mutant Huntingtin protein expression in living cells by a newly identified RNA CAG binder
Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum
Characterization of the CagT4SS proteins CagN and CagM
Huntingtin assoziierte Proteine
Huntingtin Lowering Strategies
Julius, C.A.G.
Huntingtin CAG repeat size variations below the Huntington’s disease threshold: associations with depression, anxiety and basal ganglia structure
Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome
Monitoring homology search during DNA double-strand break repair in vivo
Monitoring homology search during DNA double-strand break repair in vivo
Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Correction: Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Reducing mutant Huntingtin protein expression in living cells by a newly identified RNA CAG binder
Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum
Characterization of the CagT4SS proteins CagN and CagM
Huntingtin assoziierte Proteine
Huntingtin Lowering Strategies
Julius, C.A.G.