The Parkinson's disease and restless legs syndrome/Willis-Ekbom disorder link: evidences, biases and clinical relevance

Abstract: Parkinson's disease (PD) and restless legs syndrome/Willis-Ekbom disorder (RLS/WED) are relatively common diseases in the realm of movement disorders. The fact that both may, as expected, co-occur and typically share a similar remarkable response to dopaminergic treatment raised the interest in exploration of additional shared features that throughout the years cruised fields as diverse as phenomenology, epidemiology, genetics, pathology, and clinical studies. In this review, we describe and critically examine the evidence and biases of a conceivable overlap of these two disorders, trying to shed light onto two main sources of confusion: (1) are PD and RLS/WED reciprocal risk factors? and (2) what are the main mimics of RLS/WED in PD?

Object Details

• Alternative title: A conexo doena de Parkinson: sndrome das pernas inquietas/doena de Willis-Ekbom: evidncias, vieses e relevncia clnica
• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: The Parkinson's disease and restless legs syndrome/Willis-Ekbom disorder link: evidences, biases and clinical relevance ; volume:77 ; number:01 ; year:2019 ; pages:47-54 ; Arquivos de neuro-psiquiatria ; 77, Heft 01 (2019), 47-54

Contributors, Places and Time

• Contributor: Munhoz, Renato Puppi ; Constantino, Maria C. L. ; Silveira-Moriyama, Laura

Further information

• DOI: 10.1590/0004-282X20180125
• URN: urn:nbn:de:101:1-2023100511574623291407
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:54 AM CEST