Delayed graft function after renal transplantation
Background information: Delayed graft function (DGF), defined as the need for dialysis within the first week of a kidney transplant, is a common complication, particularly in extended criteria donor transplants, where its incidence ranges from 21 to 31%. Objectives: We observed a prolonged case of DGF in a 47-year-old patient with chronic kidney disease (CKD) resulting from diabetic nephropathy. The patient, classified in a moderate immunologic mismatch group, received a marginal deceased donor kidney. Results: For the first 4 weeks post-transplantation, graft function was impaired. After 29 days of anuria, the transplanted kidney began to recover. The literature review found few clinical cases of DGF extending beyond 1 month. Our patient had several risk factors for DGF, including diabetes mellitus, pre-transplant hemodialysis, and moderate immunologic mismatch. Additionally, the marginal graft increased the risk of ischemia-reperfusion injury and glycocalyx damage. However, it remains unclear how these factors influenced the duration of DGF. The exact cause of the extended DGF in this case remains unknown. Although the literature identifies key risk factors for DGF, data on factors leading to prolonged kidney dysfunction are lacking. Therefore, decisions to remove a non-functioning transplanted kidney should not be made hastily.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Delayed graft function after renal transplantation ; volume:20 ; number:1 ; year:2025 ; extent:6
Open medicine ; 20, Heft 1 (2025) (gesamt 6)
- Creator
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Skaudickas, Darijus
Lenčiauskas, Povilas
Skaudickas, Augustas
Bura, Andrejus
- DOI
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10.1515/med-2025-1140
- URN
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urn:nbn:de:101:1-2503040423249.429307188738
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:28 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Skaudickas, Darijus
- Lenčiauskas, Povilas
- Skaudickas, Augustas
- Bura, Andrejus
Other Objects (12)
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An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors
Prediction of delayed graft function by early salivary microbiota following kidney transplantation
Duration of delayed graft function and its impact on graft outcomes in deceased donor kidney transplantation
Donor caveolin 1 (CAV1) genetic polymorphism influences graft function after renal transplantation
Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients
Cell death biomarkers as early predictors for delayed graft function in patients following kidney transplantation
Pre-transplant HLA antibodies and delayed graft function in the current era of kidney transplantation
Results of Renal Transplantation on Alloplastic Arterial Grafts
Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: a prospective study
Increased resistin in brain dead organ donors is associated with delayed graft function after kidney transplantation
Prediction of delayed graft function after kidney transplantation: comparison between logistic regression and machine learning methods
Predictors of Delayed Graft Function in Renal Transplantation
An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors
Prediction of delayed graft function by early salivary microbiota following kidney transplantation
Duration of delayed graft function and its impact on graft outcomes in deceased donor kidney transplantation
Donor caveolin 1 (CAV1) genetic polymorphism influences graft function after renal transplantation
Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients
Cell death biomarkers as early predictors for delayed graft function in patients following kidney transplantation
Pre-transplant HLA antibodies and delayed graft function in the current era of kidney transplantation
Results of Renal Transplantation on Alloplastic Arterial Grafts
Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: a prospective study
Increased resistin in brain dead organ donors is associated with delayed graft function after kidney transplantation
Prediction of delayed graft function after kidney transplantation: comparison between logistic regression and machine learning methods
Predictors of Delayed Graft Function in Renal Transplantation
An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors
Prediction of delayed graft function by early salivary microbiota following kidney transplantation
Duration of delayed graft function and its impact on graft outcomes in deceased donor kidney transplantation
Donor caveolin 1 (CAV1) genetic polymorphism influences graft function after renal transplantation
Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients
Cell death biomarkers as early predictors for delayed graft function in patients following kidney transplantation
Pre-transplant HLA antibodies and delayed graft function in the current era of kidney transplantation
Results of Renal Transplantation on Alloplastic Arterial Grafts
Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: a prospective study
Increased resistin in brain dead organ donors is associated with delayed graft function after kidney transplantation