A Triazole‐Substituted Aryl Iodide with Omnipotent Reactivity in Enantioselective Oxidations †

Abstract: A widely applicable triazole‐substituted chiral aryl iodide is described as catalyst for enantioselective oxidation reactions. The introduction of a substituent in ortho‐position to the iodide is key for its high reactivity and selectivity. Besides a robust and modular synthesis, the main advantage of this catalyst is the excellent performance in a plethora of mechanistically diverse enantioselective transformations, such as spirocyclizations, phenol dearomatizations, α‐oxygenations, and oxidative rearrangements. DFT‐calculations of in situ generated [hydroxy (tosyloxy) iodo]arene isomers give an initial rational for the observed reactivity.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: A Triazole‐Substituted Aryl Iodide with Omnipotent Reactivity in Enantioselective Oxidations † ; volume:59 ; number:4 ; year:2020 ; pages:1479-1484 ; extent:6 ; Angewandte Chemie / International edition. International edition ; 59, Heft 4 (2020), 1479-1484 (gesamt 6)

Beteiligte, Orts- und Zeitangaben

• Urheber: Abazid, Ayham H. ; Nachtsheim, Boris J.

Weitere Informationen

• DOI: 10.1002/anie.201912023
• URN: urn:nbn:de:101:1-2022061313521324287161
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 15.08.2025, 07:23 MESZ