Risk of parenteral nutrition in neonates - an overview

Abstract: Healthcare-associated infections (HAI) in preterm infants are a challenge to the care of these fragile patients. HAI-incidence rates range from 6 to 27 infections per 1000 patient-days. Most nosocomial infections are bloodstream infections and of these, the majority is associated with the use of central venous catheters. Many studies identified parenteral nutrition as an independent risk factor for HAI, catheter-associated bloodstream infection, and clinical sepsis. This fact and various published outbreaks due to contaminated parenteral nutrition preparations highlight the importance of appropriate standards in the preparation and handling of intravenous solutions and parenteral nutrition. Ready-to-use parenteral nutrition formulations may provide additional safety in this context. However, there is concern that such formulations may result in overfeeding and necrotizing enterocolitis. Given the risk for catheter-associated infection, handling with parenteral nutrition should be minimized and the duration shortened. Further research is required about this topic

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Nutrients. - 4, 10 (2012) , 1490-1503, ISSN: 2072-6643

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2021
Creator
Zingg, Walter
Tomaske, Maren
Martin, Maria

DOI
10.3390/nu4101490
URN
urn:nbn:de:bsz:25-freidok-2227126
Rights
Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:45 PM CET

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Associated

Time of origin

  • 2021

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