The therapeutic significance of mutational signatures from DNA repair deficiency in cancer

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2041-1723

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: The therapeutic significance of mutational signatures from DNA repair deficiency in cancer ; volume:9 ; number:1 ; day:17 ; month:8 ; year:2018 ; pages:1-12 ; date:12.2018
Nature Communications ; 9, Heft 1 (17.8.2018), 1-12, 12.2018

Creator: Ma, Jennifer

Contributor: Setton, Jeremy
Lee, Nancy Y.
Riaz, Nadeem
Powell, Simon N.
SpringerLink (Online service)

DOI: 10.1038/s41467-018-05228-y

URN: urn:nbn:de:101:1-2018102714192606520647

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:48 AM CEST

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Ma, Jennifer
Setton, Jeremy
Lee, Nancy Y.
Riaz, Nadeem
Powell, Simon N.
SpringerLink (Online service)

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The therapeutic significance of mutational signatures from DNA repair deficiency in cancer

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Other Objects (12)

DNA nicks induce mutational signatures associated with BRCA1 deficiency

Mutational signatures are jointly shaped by DNA damage and repair

Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair

Mutational signatures in colon cancer

Mutational signatures reveal ternary relationships between homologous recombination repair, APOBEC, and mismatch repair in gynecological cancers

Mutational signatures of genotoxic cancer therapies

Mutational signatures: experimental design and analytical framework

Mutational signatures among young-onset testicular cancers

Signatures of mutational processes in human cancer

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

Mutational Signatures in Cancer (MuSiCa): a web application to implement mutational signatures analysis in cancer samples

SigsPack, a package for cancer mutational signatures

DNA nicks induce mutational signatures associated with BRCA1 deficiency

Mutational signatures are jointly shaped by DNA damage and repair

Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair

Mutational signatures in colon cancer

Mutational signatures reveal ternary relationships between homologous recombination repair, APOBEC, and mismatch repair in gynecological cancers

Mutational signatures of genotoxic cancer therapies

Mutational signatures: experimental design and analytical framework

Mutational signatures among young-onset testicular cancers

Signatures of mutational processes in human cancer

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

Mutational Signatures in Cancer (MuSiCa): a web application to implement mutational signatures analysis in cancer samples

SigsPack, a package for cancer mutational signatures

DNA nicks induce mutational signatures associated with BRCA1 deficiency

Mutational signatures are jointly shaped by DNA damage and repair

Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair

Mutational signatures in colon cancer

Mutational signatures reveal ternary relationships between homologous recombination repair, APOBEC, and mismatch repair in gynecological cancers

Mutational signatures of genotoxic cancer therapies

Mutational signatures: experimental design and analytical framework

Mutational signatures among young-onset testicular cancers

Signatures of mutational processes in human cancer

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

Mutational Signatures in Cancer (MuSiCa): a web application to implement mutational signatures analysis in cancer samples

SigsPack, a package for cancer mutational signatures

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