IFN-α confers epigenetic regulation of HBV cccDNA minichromosome by modulating GCN5-mediated succinylation of histone H3K79 to clear HBV cccDNA

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1868-7083

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: IFN-α confers epigenetic regulation of HBV cccDNA minichromosome by modulating GCN5-mediated succinylation of histone H3K79 to clear HBV cccDNA ; volume:12 ; number:1 ; day:7 ; month:9 ; year:2020 ; pages:1-16 ; date:12.2020
Clinical epigenetics ; 12, Heft 1 (7.9.2020), 1-16, 12.2020

Creator: Yuan, Ying
Yuan, Hongfeng
Yang, Guang
Yun, Haolin
Zhao, Man
Liu, Zixian
Zhao, Lina
Geng, Yu
Liu, Lei
Wang, Jiapei
Zhang, Huihui
Wang, Yufei
Zhang, Xiao-dong

Contributor: SpringerLink (Online service)

DOI: 10.1186/s13148-020-00928-z

URN: urn:nbn:de:101:1-2020102719130358783440

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:20 AM CEST

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Associated

Yuan, Ying
Yuan, Hongfeng
Yang, Guang
Yun, Haolin
Zhao, Man
Liu, Zixian
Zhao, Lina
Geng, Yu
Liu, Lei
Wang, Jiapei
Zhang, Huihui
Wang, Yufei
Zhang, Xiao-dong
SpringerLink (Online service)

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IFN-α confers epigenetic regulation of HBV cccDNA minichromosome by modulating GCN5-mediated succinylation of histone H3K79 to clear HBV cccDNA

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Other Objects (12)

Reduced HBV cccDNA and HBsAg in HBV-associated hepatocellular carcinoma tissues

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Serum HBV RNA correlated with intrahepatic cccDNA more strongly than other HBV markers during peg-interferon treatment

Dynamics of HBV cccDNA expression and transcription in different cell growth phase

Baseline value of intrahepatic HBV DNA over cccDNA predicts patient’s response to interferon therapy

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