Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1432-0533

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology ; day:30 ; month:4 ; year:2016 ; pages:1-20
Acta neuropathologica ; (30.4.2016), 1-20

Creator: Lauritzen, Inger

Contributor: Pardossi-Piquard, Raphaëlle
Bourgeois, Alexandre
Pagnotta, Sophie
Biferi, Maria-Grazia
Barkats, Martine
Lacor, Pascale
Klein, William
Bauer, Charlotte
Checler, Frederic
SpringerLink (Online service)

DOI: 10.1007/s00401-016-1577-6

URN: urn:nbn:de:1111-2016050414830

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:58 AM CEST

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Associated

Lauritzen, Inger
Pardossi-Piquard, Raphaëlle
Bourgeois, Alexandre
Pagnotta, Sophie
Biferi, Maria-Grazia
Barkats, Martine
Lacor, Pascale
Klein, William
Bauer, Charlotte
Checler, Frederic
SpringerLink (Online service)

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Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology

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Other Objects (12)

Triamterene induces autophagic degradation of lysosome by exacerbating lysosomal integrity

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Lysosomal Ca2+ release-facilitated TFEB nuclear translocation alleviates ischemic brain injury by attenuating autophagic/lysosomal dysfunction in neurons

Lysosomal gene ATP6AP1 promotes doxorubicin resistance via up-regulating autophagic flux in breast cancer

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology

N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction

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Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

Triamterene induces autophagic degradation of lysosome by exacerbating lysosomal integrity

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Alpha-Hederin induces incomplete autophagic injury in non-small cell lung cancer by interfering with the lysosomal acidification

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Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

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