Emerging Computational Methods in Mass Spectrometry Imaging

Abstract: Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of hundreds of molecules in biological samples with high sensitivity and molecular specificity. Advanced MSI platforms with capability of high‐spatial resolution and high‐throughput acquisition generate vast amount of data, which necessitates the development of computational tools for MSI data analysis. In addition, computation‐driven MSI experiments have recently emerged as enabling technologies for further improving the MSI capabilities with little or no hardware modification. This review provides a critical summary of computational methods and resources developed for MSI data analysis and interpretation along with computational approaches for improving throughput and molecular coverage in MSI experiments. This review is focused on the recently developed artificial intelligence methods and provides an outlook for a future paradigm shift in MSI with transformative computational methods.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Emerging Computational Methods in Mass Spectrometry Imaging ; day:17 ; month:10 ; year:2022 ; extent:20
Advanced science ; (17.10.2022) (gesamt 20)

Urheber
Hu, Hang
Laskin, Julia

DOI
10.1002/advs.202203339
URN
urn:nbn:de:101:1-2022101815495515598872
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:21 MESZ

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Beteiligte

  • Hu, Hang
  • Laskin, Julia

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