Severe Toxic Epidermal Necrolysis and Drug Reaction with Eosinophilia and Systemic Symptoms Overlap Syndrome Treated with Benralizumab: A Case Report

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TEN/DRESS overlap syndrome can be difficult to diagnose, especially if it is masked by comorbidities in critically ill patients in intensive care units. The existing therapy for the two conditions is also a major challenge for the treating team. A possible alternative, especially for refractory cases, is benralizumab as an IL-5-receptor alpha-chain-specific humanized monoclonal antibody (IgG1k). We are able to show a successful treatment in this case report.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Severe Toxic Epidermal Necrolysis and Drug Reaction with Eosinophilia and Systemic Symptoms Overlap Syndrome Treated with Benralizumab: A Case Report ; volume:14 ; number:2 ; year:2022 ; pages:203-209 ; extent:7
Case reports in dermatology ; 14, Heft 2 (2022), 203-209 (gesamt 7)

Creator
Zeller, Felix K.
Bader, Patrick R.
Nägeli, Mirjam C.
Buehler, Philipp K.
Schuepbach, Reto A.

DOI
10.1159/000525752
URN
urn:nbn:de:101:1-2022092201050020193327
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:20 AM CEST

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Associated

  • Zeller, Felix K.
  • Bader, Patrick R.
  • Nägeli, Mirjam C.
  • Buehler, Philipp K.
  • Schuepbach, Reto A.

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