Journal article | Zeitschriftenartikel

Phenomenology, socio-demographic factors and outcome upon discharge of manic and mixed episodes in hospitalized adolescents

Background: The existence of bipolar disorder type I (BD-I) during adolescence is now clearly established whereas there are still some controversies on BD-II and BD-NOS diagnosis, mainly in Europe (O'Dowd in Br Med J 29, 2006). Little is known on the phenomenology and potential short-term prognosis factors of bipolar episodes in this age population. In particular, very few studies examine this issue on inpatients in the European context of free access to care. Objective: To describe the phenomenology of acute manic and mixed episodes in hospitalized adolescents and to analyse potential predictive factors associated with clinical improvement at discharge and length of hospitalization. Methods: A total of 80 subjects, aged 12–20 years, consecutively hospitalized for a manic or mixed episode. Socio-demographic and clinical data were extracted by reviewing patients' charts. We used a multivariate analysis to evaluate short-term outcome predictors. Results: The sample was characterized by severe impairment, high rates of psychotic features (N = 50, 62.5%), a long duration of stay (mean 80.4 days), and an overall good improvement (86% very much or much improved). Thirty-three (41.3 %) patients had a history of depressive episodes, 13 (16.3%) had manic or brief psychotic episodes but only 3 (3.7%) had a history of attention deficit/ hyperactivity disorders. More manic episodes than mixed episodes were identified in subjects with mental retardation (MR) and in subjects from migrant and/or low socio-economic families. Overall severity and female gender predicted better improvement in GAF scores. Poor insight and the existence of psychotic features predicted longer duration of stay. Conclusion: These results suggest that severe manic and mixed episodes in adolescents with BD-I need prolonged inpatient care to improve and that socio-cultural factors and MR should be examined more closely in youth with BD.

Phenomenology, socio-demographic factors and outcome upon discharge of manic and mixed episodes in hospitalized adolescents

Urheber*in: Brunelle, Julie; Consoli, Angèle; Tanguy, Marie-Laure; Huynh, Christophe; Perisse, Didier; Deniau, Emmanuelle; Guilé, Jean-Marc; Gérardin, Priscille; Cohen, David

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Umfang
Seite(n): 185-193
Sprache
Englisch
Anmerkungen
Status: Postprint; begutachtet (peer reviewed)

Erschienen in
European Child & Adolescent Psychiatry, 18(3)

Thema
Psychologie
psychische Störungen, Behandlung und Prävention

Ereignis
Geistige Schöpfung
(wer)
Brunelle, Julie
Consoli, Angèle
Tanguy, Marie-Laure
Huynh, Christophe
Perisse, Didier
Deniau, Emmanuelle
Guilé, Jean-Marc
Gérardin, Priscille
Cohen, David
Ereignis
Veröffentlichung
(wo)
Deutschland
(wann)
2009

DOI
URN
urn:nbn:de:0168-ssoar-122937
Rechteinformation
GESIS - Leibniz-Institut für Sozialwissenschaften. Bibliothek Köln
Letzte Aktualisierung
21.06.2024, 16:26 MESZ

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Objekttyp

  • Zeitschriftenartikel

Beteiligte

  • Brunelle, Julie
  • Consoli, Angèle
  • Tanguy, Marie-Laure
  • Huynh, Christophe
  • Perisse, Didier
  • Deniau, Emmanuelle
  • Guilé, Jean-Marc
  • Gérardin, Priscille
  • Cohen, David

Entstanden

  • 2009

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