Journal article | Zeitschriftenartikel
Phenomenology, socio-demographic factors and outcome upon discharge of manic and mixed episodes in hospitalized adolescents
Background: The existence of bipolar disorder type I (BD-I) during adolescence is now clearly established whereas there are still some controversies on BD-II and BD-NOS diagnosis, mainly in Europe (O'Dowd in Br Med J 29, 2006). Little is known on the phenomenology and potential short-term prognosis factors of bipolar episodes in this age population. In particular, very few studies examine this issue on inpatients in the European context of free access to care. Objective: To describe the phenomenology of acute manic and mixed episodes in hospitalized adolescents and to analyse potential predictive factors associated with clinical improvement at discharge and length of hospitalization. Methods: A total of 80 subjects, aged 12–20 years, consecutively hospitalized for a manic or mixed episode. Socio-demographic and clinical data were extracted by reviewing patients' charts. We used a multivariate analysis to evaluate short-term outcome predictors. Results: The sample was characterized by severe impairment, high rates of psychotic features (N = 50, 62.5%), a long duration of stay (mean 80.4 days), and an overall good improvement (86% very much or much improved). Thirty-three (41.3 %) patients had a history of depressive episodes, 13 (16.3%) had manic or brief psychotic episodes but only 3 (3.7%) had a history of attention deficit/ hyperactivity disorders. More manic episodes than mixed episodes were identified in subjects with mental retardation (MR) and in subjects from migrant and/or low socio-economic families. Overall severity and female gender predicted better improvement in GAF scores. Poor insight and the existence of psychotic features predicted longer duration of stay. Conclusion: These results suggest that severe manic and mixed episodes in adolescents with BD-I need prolonged inpatient care to improve and that socio-cultural factors and MR should be examined more closely in youth with BD.
- Umfang
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Seite(n): 185-193
- Sprache
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Englisch
- Anmerkungen
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Status: Postprint; begutachtet (peer reviewed)
- Erschienen in
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European Child & Adolescent Psychiatry, 18(3)
- Thema
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Psychologie
psychische Störungen, Behandlung und Prävention
- Ereignis
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Geistige Schöpfung
- (wer)
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Brunelle, Julie
Consoli, Angèle
Tanguy, Marie-Laure
Huynh, Christophe
Perisse, Didier
Deniau, Emmanuelle
Guilé, Jean-Marc
Gérardin, Priscille
Cohen, David
- Ereignis
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Veröffentlichung
- (wo)
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Deutschland
- (wann)
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2009
- DOI
- URN
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urn:nbn:de:0168-ssoar-122937
- Rechteinformation
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GESIS - Leibniz-Institut für Sozialwissenschaften. Bibliothek Köln
- Letzte Aktualisierung
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21.06.2024, 16:26 MESZ
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Objekttyp
- Zeitschriftenartikel
Beteiligte
- Brunelle, Julie
- Consoli, Angèle
- Tanguy, Marie-Laure
- Huynh, Christophe
- Perisse, Didier
- Deniau, Emmanuelle
- Guilé, Jean-Marc
- Gérardin, Priscille
- Cohen, David
Entstanden
- 2009