Significance of negative cervical cytology and positive HPV in the diagnosis of cervical lesions by colposcopy
Objective: The aim of this study was to investigate the significance of colposcopy in diagnosing cervical lesions when negative cervical cytology is combined with positive human papillomavirus (HPV). Methods: Overall, 370 patients with cervical epithelial lesions who had negative cervical fluid-based cytology combined with positive HPV results were selected and analysed for severity of cervical lesions and HPV distribution. Results: Among the patients with cervical lesions, 242 had a single HPV infection, and 128 cases had multiple infections. No significant difference was found between HPV single infection and multiple infections in both groups of patients with cervical lesions (P > 0.05). Furthermore, 137 had non-HPV 16 and 18, accounting for 37.30% of all the patients with cervical lesions. Among them, HPV 52, 58, and 33 infections were the most common at 38.69, 30.66 and 29.20%, respectively – significantly higher than other high-risk HPV types (P < 0.05). Conclusion: High-risk HPV testing is crucial in patients with negative cervical fluid-based cytology combined with positive HPV results. Patients with HPV 16 and 18 and those with simple HPV 52, 58, and 33 infections should undergo timely colposcopy.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Significance of negative cervical cytology and positive HPV in the diagnosis of cervical lesions by colposcopy ; volume:19 ; number:1 ; year:2024 ; extent:6
Open medicine ; 19, Heft 1 (2024) (gesamt 6)
- Creator
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Zhang, Changhong
Dong, Liu
Liu, Kejie
Xiao, Hong
Si, Hao
Wang, Xiaoqin
Wang, Hui
- DOI
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10.1515/med-2024-1051
- URN
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urn:nbn:de:101:1-2410041547586.535665805365
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:29 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Zhang, Changhong
- Dong, Liu
- Liu, Kejie
- Xiao, Hong
- Si, Hao
- Wang, Xiaoqin
- Wang, Hui
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