Endoscopic optical coherence tomography angiography using a forward imaging piezo scanner probe

Abstract: A forward imaging endoscope for optical coherence tomography angiography (OCTA) featuring a piezoelectric fiber scanner is presented. Imaging is performed with an optical coherence tomography (OCT) system incorporating an akinetic light source with a center wavelength of 1300 nm, bandwidth of 90 nm and A-line rate of 173 kHz. The endoscope operates in contact mode to avoid motion artifacts, in particular, beneficial for OCTA measurements, and achieves a transversal resolution of 12 μm in air at a rigid probe size of 4 mm in diameter and 11.3 mm in length. A spiral scan pattern is generated at a scanning frequency of 360 Hz to sample a maximum field of view of 1.3 mm. OCT images of a human finger as well as visualization of microvasculature of the human palm are presented both in two and three dimensions. The combination of morphological tissue contrast with qualitative dynamic blood flow information within this endoscopic imaging approach potentially enables improved early diagnostic capabilities of internal organs for diseases such as bladder cancer

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Journal of biophotonics. - 12, 4 (2019) , e201800382, ISSN: 1864-063X

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2020
Creator
Wurster, Lara M.
Shah, Ronak Narendra
Placzek, Fabian
Kretschmer, Simon
Niederleithner, Michael
Ginner, Laurin
Ensher, Jason
Minneman, Michael P.
Hoover, Erich E.
Zappe, Hans P.
Drexler, Wolfgang
Leitgeb, Rainer A.
Ataman, Çağlar

DOI
10.1002/jbio.201800382
URN
urn:nbn:de:bsz:25-freidok-1526144
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:43 PM CET

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Associated

Time of origin

  • 2020

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