Postpartum hemorrhage in the setting of a mechanical heart valve

Background:: Therapeutic anticoagulation is required for all patients with prosthetic mitral valves. Anticoagulation with warfarin is recommended; however, warfarin is teratogenic in early pregnancy and therefore alternate anticoagulation regimens are suggested for pregnant patients. Case:: A 28-year-old gravida 2, para 1 woman at 36 weeks’ gestation with a prosthetic mitral valve and a history of a corrected anomalous origin of the left coronary artery arising from the left pulmonary artery presented in labor. She underwent a spontaneous vaginal delivery complicated by a postpartum hemorrhage necessitating a hysterectomy. Conclusion:: Management of mechanical valves in pregnancy is controversial. The provider must weigh the risks of life threatening valve thrombosis and malfunction against the risk of significant hemorrhage. This case report reviews peripartum anticoagulation protocols and management of massive hemorrhage in patients with prosthetic mechanical valves.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Postpartum hemorrhage in the setting of a mechanical heart valve ; volume:5 ; number:2 ; year:2016 ; pages:93-96 ; extent:4 ; Case reports in perinatal medicine ; 5, Heft 2 (2016), 93-96 (gesamt 4)

Contributors, Places and Time

• Creator: Perdigao, Joana Lopes ; McQueen, Dana ; Nunes, Kenneth ; DiGiovanni, Laura

Further information

• DOI: 10.1515/crpm-2015-0102
• URN: urn:nbn:de:101:1-2411121528089.844627199799
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:32 AM CEST