Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2049-3002

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells ; volume:9 ; number:1 ; day:22 ; month:1 ; year:2021 ; pages:1-17 ; date:12.2021
Cancer & metabolism ; 9, Heft 1 (22.1.2021), 1-17, 12.2021

Creator: Almouhanna, Fadi
Blagojević, Biljana
Can, Suzan
Ghanem, Ali
Wölfl, Stefan

Contributor: SpringerLink (Online service)

DOI: 10.1186/s40170-021-00239-8

URN: urn:nbn:de:101:1-2021031418115970479513

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:30 AM CEST

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Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells

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Other Objects (12)

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Efavirenz induces alterations in lipid metabolism through AMPK activation

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AMPK activation attenuates inflammatory pain through inhibiting NF-κB activation and IL-1β expression

Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

TAB1 regulates glycolysis and activation of macrophages in diabetic nephropathy

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