Ultrasound-guided transperineal vs transrectal prostate biopsy: A meta-analysis of diagnostic accuracy and complication rates

Objectives: We conducted a systematic review to compare the diagnostic utility of ultrasound-guided transperineal (TP) and transrectal (TR) prostate biopsy methods for prostate cancer detection. Methods: We searched PubMed, Embase, Web of Science, and Cochrane databases up to October 30, 2023, for relevant studies, screening the literature and assessing bias independently. Results: Eleven trials were analyzed using relative risk and 95% confidence intervals, with no evidence of publication bias. Diagnostic rates showed no significant difference between TP and TR biopsies (mean difference [MD]: 1.03, 95% confidence interval [CI]: 0.91–1.14, P = 0.56). Prostate volume analysis also showed no significant difference (MD: –0.07, 95% CI: –0.73 to 0.59, P < 0.0001, combined effect size P = 0.83). Similarly, PSA levels were comparable between TP and TR biopsies (MD: 0.93, 95% CI: –0.44 to 2.30, P < 0.0001, combined effect size P = 0.18). Conclusion: Both biopsy methods exhibit similar diagnostic accuracy; however, TP has a lower risk of biopsy

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Ultrasound-guided transperineal vs transrectal prostate biopsy: A meta-analysis of diagnostic accuracy and complication rates ; volume:19 ; number:1 ; year:2024 ; extent:9
Open medicine ; 19, Heft 1 (2024) (gesamt 9)

Creator
Wu, Tao
Xing, Yanchun

DOI
10.1515/med-2024-1039
URN
urn:nbn:de:101:1-2410041542169.205037684104
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:27 AM CEST

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Associated

  • Wu, Tao
  • Xing, Yanchun

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