Biotransformation of a biosynthetic intermediate mimic of nonactin by Streptomyces griseus

Abstract: A mimic of a plausible biosynthetic intermediate of bisho­mononactic acid, one of the monomers of macrotetrolide antibiotics (polynactin), was synthesized as a thiol ester. FAB-MS analysis showed that fermentation of polynactin producing Streptomyces griseus with the compound, afforded the unnatural polynactins containing bishomononactic acid (s).

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Biotransformation of a biosynthetic intermediate mimic of nonactin by Streptomyces griseus ; volume:17 ; number:3-4 ; year:2011 ; pages:93-98
Heterocyclic communications ; 17, Heft 3-4 (2011), 93-98

Creator
Hanadatea, Tadaatsu
Takaia, Kentaro
Abe, Naoki
Yamada, Teiko
Kuwahara, Shigefumi
Kiyota, Hiromasa

DOI
10.1515/hc.2011.021
URN
urn:nbn:de:101:1-2501140317573.125420728504
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:25 AM CEST

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Associated

  • Hanadatea, Tadaatsu
  • Takaia, Kentaro
  • Abe, Naoki
  • Yamada, Teiko
  • Kuwahara, Shigefumi
  • Kiyota, Hiromasa

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