Intensity and lag-time of non-pharmaceutical interventions on COVID-19 dynamics in German hospitals

Abstract: Introduction: Evaluating the potential effects of non-pharmaceutical interventions on COVID-19 dynamics is challenging and controversially discussed in the literature. The reasons are manifold, and some of them are as follows. First, interventions are strongly correlated, making a specific contribution difficult to disentangle; second, time trends (including SARS-CoV-2 variants, vaccination coverage and seasonality) influence the potential effects; third, interventions influence the different populations and dynamics with a time delay.

Methods: In this article, we apply a distributed lag linear model on COVID-19 data from Germany from January 2020 to June 2022 to study intensity and lag time effects on the number of hospital patients and the number of prevalent intensive care patients diagnosed with polymerase chain reaction tests. We further discuss how the findings depend on the complexity of accounting for the seasonal trends.

Results and discussion: Our findings show that the first reducing effect of non-pharmaceutical interventions on the number of prevalent intensive care patients before vaccination can be expected not before a time lag of 5 days; the main effect is after a time lag of 10–15 days. In general, we denote that the number of hospital and prevalent intensive care patients decrease with an increase in the overall non-pharmaceutical interventions intensity with a time lag of 9 and 10 days. Finally, we emphasize a clear interpretation of the findings noting that a causal conclusion is challenging due to the lack of a suitable experimental study design

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch
Anmerkungen
Frontiers in public health. - 11 (2023) , 1087580, ISSN: 2296-2565

Ereignis
Veröffentlichung
(wo)
Freiburg
(wer)
Universität
(wann)
2023
Urheber
Montcho, Yvette
Klingler, Paul
Lokonon, Bruno Enagnon
Tovissodé, Chénangnon Frédéric
Glele Kakaï, Romain Lucas
Wolkewitz, Martin

DOI
10.3389/fpubh.2023.1087580
URN
urn:nbn:de:bsz:25-freidok-2351034
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
25.03.2025, 13:44 MEZ

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Beteiligte

  • Montcho, Yvette
  • Klingler, Paul
  • Lokonon, Bruno Enagnon
  • Tovissodé, Chénangnon Frédéric
  • Glele Kakaï, Romain Lucas
  • Wolkewitz, Martin
  • Universität

Entstanden

  • 2023

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