Serum inflammatory cytokines comparison in gastric cancer therapy

Abstract: To compare serum inflammatory cytokines between laparoscopic-assisted and open radical gastrectomy in the perioperative period, 80 cases of advanced gastric cancer were chosen for the study. They were divided into laparoscopy group (40 cases) and abdominal open surgery group (40 cases), performed laparoscopic-assisted radical gastrostomy and conventional open radical gastrectomy, respectively. Serum Heme oxygenase-1 (HO-1), TNF-α, IL-6 and CRP were measured by ELISA on preoperative day 1, post-operative day 1 and post-operative day3. Serum HO-1, TNF-α, IL-6 and CRP had no significant difference between the laparoscopy group and the open group on pre-operative day 1. Serum HO-1, IL-6 and CRP of the laparoscopy group were significantly lower than that of the open group on post-operative day 1 and day 3 except for Serum TNF-α which had no significant difference. Laparoscopic-assisted radical gastrectomy was minimally invasive compared with conventional open radical gastrectomy in advanced gastric cancer patients.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Serum inflammatory cytokines comparison in gastric cancer therapy ; volume:14 ; number:1 ; year:2019 ; pages:300-306 ; extent:7
Open medicine ; 14, Heft 1 (2019), 300-306 (gesamt 7)

Creator
Zhang, Li
Ren, Lehao
Shan, Keshu
Guo, Xiaobo
Wang, Jinshen
Cui, Bin
An, Jie

DOI
10.1515/med-2019-0027
URN
urn:nbn:de:101:1-2022101114200970562471
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:30 AM CEST

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Associated

  • Zhang, Li
  • Ren, Lehao
  • Shan, Keshu
  • Guo, Xiaobo
  • Wang, Jinshen
  • Cui, Bin
  • An, Jie

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