4D Printing for Biomedical Applications

Abstract: 4D (bio‐) printing endows 3D printed (bio‐) materials with multiple functionalities and dynamic properties. 4D printed materials have been recently used in biomedical engineering for the design and fabrication of biomedical devices, such as stents, occluders, microneedles, smart 3D‐cell engineered microenvironments, drug delivery systems, wound closures, and implantable medical devices. However, the success of 4D printing relies on the rational design of 4D printed objects, the selection of smart materials, and the availability of appropriate types of external (multi‐) stimuli. Here, this work first highlights the different types of smart materials, external stimuli, and design strategies used in 4D (bio‐) printing. Then, it presents a critical review of the biomedical applications of 4D printing and discusses the future directions of biomedical research in this exciting area, including in vivo tissue regeneration studies, the implementation of multiple materials with reversible shape memory behaviors, the creation of fast shape‐transformation responses, the ability to operate at the microscale, untethered activation and control, and the application of (machine learning‐based) modeling approaches to predict the structure–property and design–shape transformation relationships of 4D (bio) printed constructs.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
4D Printing for Biomedical Applications ; day:28 ; month:05 ; year:2024 ; extent:34
Advanced materials ; (28.05.2024) (gesamt 34)

Urheber
Yarali, Ebrahim
Mirzaali, Mohammad J.
Ghalayaniesfahani, Ava
Accardo, Angelo
Diaz‐Payno, Pedro J.
Zadpoor, Amir A.

DOI
10.1002/adma.202402301
URN
urn:nbn:de:101:1-2405291403445.701905479177
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:58 MESZ

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Beteiligte

  • Yarali, Ebrahim
  • Mirzaali, Mohammad J.
  • Ghalayaniesfahani, Ava
  • Accardo, Angelo
  • Diaz‐Payno, Pedro J.
  • Zadpoor, Amir A.

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