Green Nail Syndrome Treated with Ozenoxacin: Two Case Reports
Green nail syndrome (GNS) is a persistent greenish pigmentation of the nail plate, originally described in 1944 by Goldman and Fox, due to Pseudomonas aeruginosa infection. Recently, pulmonary co-infection of P. aeruginosa and Achromobacter spp. has been described in patients with cystic fibrosis. Achromobacter xylosoxidans is a multidrug-resistant (MDR) pathogen involved in lung and soft tissue skin infections. Both Achromobacter xylosoxidans and P. aeruginosa are mainly found in humid environments or in water. There are no recognized co-infections due to P. aeruginosa and A. xylosoxidans in the skin and appendages. We describe two cases of GNS, the first due to P. aeruginosa associated with Achromobacter xylosoxidans; the other due to MDR P. aeruginosa, both successfully treated with topical ozenoxacin 1% cream daily for 12 weeks. The clinical management of GNS can be confusing, especially when the bacterial culture result is inconsistent or when non-Pseudomonas bacteria are isolated. In our case, due to the co-infection of P. aeruginosa and Achromobacter spp., local treatment with ozenoxacin – the first nonfluorinated quinolone – could be a safe and effective treatment in case of MDR nail infections. Further studies are required to evaluate clinical isolation from nail infections and the co-presence of P. aeruginosa and A. xylosoxidans.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Green Nail Syndrome Treated with Ozenoxacin: Two Case Reports ; volume:15 ; number:1 ; year:2023 ; pages:217-224 ; extent:8
Case reports in dermatology ; 15, Heft 1 (2023), 217-224 (gesamt 8)
- Urheber
-
Cosio, Terenzio
Petruccelli, Rosalba
Gaziano, Roberta
Fontana, Carla
Favaro, Marco
Zampini, Paola
Pistoia, Enrico Salvatore
Diluvio, Laura
Lozzi, Flavia
Bianchi, Luca
Campione, Elena
- DOI
-
10.1159/000533923
- URN
-
urn:nbn:de:101:1-2024010323192848915239
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:31 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Cosio, Terenzio
- Petruccelli, Rosalba
- Gaziano, Roberta
- Fontana, Carla
- Favaro, Marco
- Zampini, Paola
- Pistoia, Enrico Salvatore
- Diluvio, Laura
- Lozzi, Flavia
- Bianchi, Luca
- Campione, Elena
Ähnliche Objekte (12)
Green nail syndrome in a teenager
Intercondylar Synovial Septum in Two Patients with Nail-Patella Syndrome
Yellow nail syndrome: a review
Kidney disease in nail–patella syndrome
Transient yellow discoloration of the nails for differential diagnosis with yellow nail syndrome
How are podocytes affected in nail–patella syndrome?
Nail-Patella Syndrome: Optical Coherence Tomography Angiography Findings
A Case of Nail Psoriasis Successfully Treated with Intralesional Methotrexate
Distal femoral flexion deformity from growth disturbance treated with a two-level osteotomy and internal lengthening nail
Yellow nail syndrome resulting from cardiac mitral valve replacement
Prenatal diagnosis of nail patella syndrome: A case report
Effectiveness of clarithromycin in patients with yellow nail syndrome
Green nail syndrome in a teenager
Intercondylar Synovial Septum in Two Patients with Nail-Patella Syndrome
Yellow nail syndrome: a review
Kidney disease in nail–patella syndrome
Transient yellow discoloration of the nails for differential diagnosis with yellow nail syndrome
How are podocytes affected in nail–patella syndrome?
Nail-Patella Syndrome: Optical Coherence Tomography Angiography Findings
A Case of Nail Psoriasis Successfully Treated with Intralesional Methotrexate
Distal femoral flexion deformity from growth disturbance treated with a two-level osteotomy and internal lengthening nail
Yellow nail syndrome resulting from cardiac mitral valve replacement
Prenatal diagnosis of nail patella syndrome: A case report
Effectiveness of clarithromycin in patients with yellow nail syndrome
Green nail syndrome in a teenager
Intercondylar Synovial Septum in Two Patients with Nail-Patella Syndrome
Yellow nail syndrome: a review
Kidney disease in nail–patella syndrome
Transient yellow discoloration of the nails for differential diagnosis with yellow nail syndrome
How are podocytes affected in nail–patella syndrome?
Nail-Patella Syndrome: Optical Coherence Tomography Angiography Findings
A Case of Nail Psoriasis Successfully Treated with Intralesional Methotrexate
Distal femoral flexion deformity from growth disturbance treated with a two-level osteotomy and internal lengthening nail
Yellow nail syndrome resulting from cardiac mitral valve replacement
Prenatal diagnosis of nail patella syndrome: A case report