(2+2) Cycloadditions of Methylene exo ‐Glycals: Synthesis of Glycopyranosylidene‐Spiro‐Azetidine‐2‐ones (β‐Lactams) and Cyclobutanones
Abstract: [2+2] Cycloadditions of methylene exo‐glycal derivatives with chlorosulfonyl isocyanate and dichloroketene were studied in detail, investigating the effect of the carbohydrate moiety, protecting groups as well as reaction temperature on the yields of the transformations. These reactions gave new anomeric spiro‐β‐lactam and spiro‐cyclobutanone derivatives, whose structure was established by 1D and 2D NMR and MS experiments. The transformation of spiro‐cyclobutanone into spiro‐γ‐lactone was also demonstrated.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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(2+2) Cycloadditions of Methylene exo ‐Glycals: Synthesis of Glycopyranosylidene‐Spiro‐Azetidine‐2‐ones (β‐Lactams) and Cyclobutanones ; day:23 ; month:02 ; year:2023 ; extent:11
European journal of organic chemistry ; (23.02.2023) (gesamt 11)
- Urheber
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József, János
Somsák, László
Tóth, Marietta
Juhász, László
- DOI
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10.1002/ejoc.202201488
- URN
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urn:nbn:de:101:1-2023022414025584432644
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 10:58 MESZ
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Beteiligte
- József, János
- Somsák, László
- Tóth, Marietta
- Juhász, László
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