Synthesis of Bis (3‐indolyl) methanes Mediated by Potassium tert‐ Butoxide

to related objects

Abstract: The indole moiety is an important N‐heterocycle found in natural products, and a key structural component of many value‐added chemicals including pharmaceuticals. In particular, bis (3‐indolyl) methanes (BIMs) are an important subgroup of indoles, composed of two indole units. Herein, we report the development of a simple method to access BIMs derivatives in yields of up to 77 % by exploiting a tBuOK‐mediated coupling reaction of indoles and benzyl alcohols.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Synthesis of Bis (3‐indolyl) methanes Mediated by Potassium tert‐ Butoxide ; volume:12 ; number:1 ; year:2023 ; extent:7
ChemistryOpen ; 12, Heft 1 (2023) (gesamt 7)

Creator: Santos, A. Sofia
Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.

DOI: 10.1002/open.202200265

URN: urn:nbn:de:101:1-2023011814050107260075

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 23.09.20252029, 1:27 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Santos, A. Sofia
Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.

Other Objects (12)

Potassium tert-Butoxide

Sodium and Potassium tert-Butyl Peroxide Hydrates: Crystal Structure and Properties

Potassium tert-Butoxide Promoted Synthesis of 4,5-Diaryl-2H-1,2,3-triazoles from Tosylhydrazones and Nitriles

Potassium Fluoride-Mediated Deprotection of Fmoc-Amino Acid Esters: One-Pot Peptide Synthesis

Synthesis of Potassium Oligosilanides in Benzene

The potassium hydride mediated trimerization of imines

tert-Butoxide-Mediated Protodeformylative Decarbonylation of α-Quaternary Homobenzaldehydes

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Tert-butyldimethylsilyl chitosan synthesis and characterization by analytical ultracentrifugation, for archaeological wood conservation

Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2

Kapitel

Tert

Potassium tert-Butoxide

Sodium and Potassium tert-Butyl Peroxide Hydrates: Crystal Structure and Properties

Potassium tert-Butoxide Promoted Synthesis of 4,5-Diaryl-2H-1,2,3-triazoles from Tosylhydrazones and Nitriles

Potassium Fluoride-Mediated Deprotection of Fmoc-Amino Acid Esters: One-Pot Peptide Synthesis

Synthesis of Potassium Oligosilanides in Benzene

The potassium hydride mediated trimerization of imines

tert-Butoxide-Mediated Protodeformylative Decarbonylation of α-Quaternary Homobenzaldehydes

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Tert-butyldimethylsilyl chitosan synthesis and characterization by analytical ultracentrifugation, for archaeological wood conservation

Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2

Kapitel

Tert

Potassium tert-Butoxide

Sodium and Potassium tert-Butyl Peroxide Hydrates: Crystal Structure and Properties

Potassium tert-Butoxide Promoted Synthesis of 4,5-Diaryl-2H-1,2,3-triazoles from Tosylhydrazones and Nitriles

Potassium Fluoride-Mediated Deprotection of Fmoc-Amino Acid Esters: One-Pot Peptide Synthesis

Synthesis of Potassium Oligosilanides in Benzene

The potassium hydride mediated trimerization of imines

tert-Butoxide-Mediated Protodeformylative Decarbonylation of α-Quaternary Homobenzaldehydes

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Tert-butyldimethylsilyl chitosan synthesis and characterization by analytical ultracentrifugation, for archaeological wood conservation

Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2

Kapitel

Tert

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read the terms of use and the privacy policy for the collection of personal data and accept them. *

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

Synthesis of Bis (3‐indolyl) methanes Mediated by Potassium tert‐ Butoxide

Object Details

References and Relationships

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

Potassium tert-Butoxide

Sodium and Potassium tert-Butyl Peroxide Hydrates: Crystal Structure and Properties

Potassium tert-Butoxide Promoted Synthesis of 4,5-Diaryl-2H-1,2,3-triazoles from Tosylhydrazones and Nitriles

Potassium Fluoride-Mediated Deprotection of Fmoc-Amino Acid Esters: One-Pot Peptide Synthesis

Synthesis of Potassium Oligosilanides in Benzene

The potassium hydride mediated trimerization of imines

tert-Butoxide-Mediated Protodeformylative Decarbonylation of α-Quaternary Homobenzaldehydes

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Tert-butyldimethylsilyl chitosan synthesis and characterization by analytical ultracentrifugation, for archaeological wood conservation

Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2

Tert

Potassium tert-Butoxide

Sodium and Potassium tert-Butyl Peroxide Hydrates: Crystal Structure and Properties

Potassium tert-Butoxide Promoted Synthesis of 4,5-Diaryl-2H-1,2,3-triazoles from Tosylhydrazones and Nitriles

Potassium Fluoride-Mediated Deprotection of Fmoc-Amino Acid Esters: One-Pot Peptide Synthesis

Synthesis of Potassium Oligosilanides in Benzene

The potassium hydride mediated trimerization of imines

tert-Butoxide-Mediated Protodeformylative Decarbonylation of α-Quaternary Homobenzaldehydes

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Tert-butyldimethylsilyl chitosan synthesis and characterization by analytical ultracentrifugation, for archaeological wood conservation

Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2

Tert

Potassium tert-Butoxide

Sodium and Potassium tert-Butyl Peroxide Hydrates: Crystal Structure and Properties

Potassium tert-Butoxide Promoted Synthesis of 4,5-Diaryl-2H-1,2,3-triazoles from Tosylhydrazones and Nitriles

Potassium Fluoride-Mediated Deprotection of Fmoc-Amino Acid Esters: One-Pot Peptide Synthesis

Synthesis of Potassium Oligosilanides in Benzene

The potassium hydride mediated trimerization of imines

tert-Butoxide-Mediated Protodeformylative Decarbonylation of α-Quaternary Homobenzaldehydes

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Hydroalkylation of Vinylarenes by Transition‐Metal‐Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert ‐Butoxide

Tert-butyldimethylsilyl chitosan synthesis and characterization by analytical ultracentrifugation, for archaeological wood conservation

Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2

Tert

Related objects

Reset password