Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- ISSN
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1465-542X
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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online resource.
- Erschienen in
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Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer ; volume:24 ; number:1 ; day:17 ; month:6 ; year:2022 ; pages:1-19 ; date:12.2022
Breast cancer research ; 24, Heft 1 (17.6.2022), 1-19, 12.2022
- Urheber
-
Ratz, Leonie
Brambillasca, Chiara
Bartke, Leandra
Huetzen, Maxim A.
Goergens, Jonas
Leidecker, Orsolya
Jachimowicz, Ron D.
Ven, Marieke van de
Proost, Natalie
Siteur, Bjørn
Korte-Grimmerink, Renske de
Bouwman, Peter
Pulver, Emilia M.
Bruijn, Roebi de
Isensee, Jörg
Hucho, Tim
Pandey, Gaurav
Lohuizen, Maarten van
Mallmann, Peter
Reinhardt, Hans Christian
Jonkers, Jos
Puppe, Julian
- Beteiligte Personen und Organisationen
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SpringerLink (Online service)
- DOI
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10.1186/s13058-022-01534-y
- URN
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urn:nbn:de:101:1-2022081623423750917206
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:25 MESZ
Datenpartner
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Beteiligte
- Ratz, Leonie
- Brambillasca, Chiara
- Bartke, Leandra
- Huetzen, Maxim A.
- Goergens, Jonas
- Leidecker, Orsolya
- Jachimowicz, Ron D.
- Ven, Marieke van de
- Proost, Natalie
- Siteur, Bjørn
- Korte-Grimmerink, Renske de
- Bouwman, Peter
- Pulver, Emilia M.
- Bruijn, Roebi de
- Isensee, Jörg
- Hucho, Tim
- Pandey, Gaurav
- Lohuizen, Maarten van
- Mallmann, Peter
- Reinhardt, Hans Christian
- Jonkers, Jos
- Puppe, Julian
- SpringerLink (Online service)
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Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma
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BRCA1 deficient mammary tumors are dependent on EZH2 expression and sensitive to polycomp repressive complex 2-inhibitor 3-deazaneplanocin A
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A
Inhibition of ATM kinase rescues planarian regeneration after lethal radiation
Funktionelle und mechanistische Charakterisierung von EZH2 in Atm-defizienten Subtypen des Pankreaskarzinoms
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PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency
Polθ: emerging synthetic lethal partner in homologous recombination-deficient tumors
Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity
Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice
Gadd45a deletion aggravates hematopoietic stem cell dysfunction in ATM-deficient mice
Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma
Drug combination studies of EZH2 inhibition combined with ATM, PI3-Kinase and CDK inhibitors in BRCA1-deficient breast tumors
BRCA1 deficient mammary tumors are dependent on EZH2 expression and sensitive to polycomp repressive complex 2-inhibitor 3-deazaneplanocin A
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A
Inhibition of ATM kinase rescues planarian regeneration after lethal radiation
Funktionelle und mechanistische Charakterisierung von EZH2 in Atm-defizienten Subtypen des Pankreaskarzinoms
The biology and molecular vulnerabilities of ATM-deficient cancers
PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency
Polθ: emerging synthetic lethal partner in homologous recombination-deficient tumors
Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity
Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice