Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal

Abstract: The acoustic cavitation phenomenon constitutes a potential hazard in ultrasound diagnostics and therapy so that early and effective detection of cavitation is of great interest. However, cavitation might even bring a higher risk especially when an echocontrast agent based on microbubbles is used. The major goal of the present work was to develop a cavitation detection method based on increased level of cavitation noise in the range of low frequencies (about 1 Hz). This method was applied in vitro using a model of body fluid containing a model echocontrast agent, such as 5% solution of lyophilized egg albumin, which was sonicated by ultrasound disintegrator. Ultrasound signal evokes cavitation in microbubble suspension accompanied by a certain level of cavitation acoustic noise. The level of noise voltage increased in the frequency range of 0.1 to 2 Hz in the presence of cavitation. Hence, this method makes it possible to determine the value of cavitation threshold. In addition, we examined how the cavitation threshold is affected by temperature and viscosity. It was found that the cavitation threshold decreased with growing temperature while it increased with growing viscosity.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal ; volume:2 ; number:2 ; year:2007 ; pages:213-221 ; extent:9
Open life sciences ; 2, Heft 2 (2007), 213-221 (gesamt 9)

Urheber
Brabec, Kamil
Mornstein, Vojtĕch

DOI
10.2478/s11535-007-0013-2
URN
urn:nbn:de:101:1-2409201831147.303180619907
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:30 MESZ

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Beteiligte

  • Brabec, Kamil
  • Mornstein, Vojtĕch

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