Durable Response to Pazopanib in a Patient with Fumarate Hydratase-Mutant Tubulocystic Renal Cell Carcinoma
Tubulocystic carcinoma of the kidney (TC-RCC) is a rare renal tumor and has been recently included as a distinct entity in WHO classification of renal neoplasms. We report the case of a patient with metastatic tubulocystic RCC whose disease progressed through standard of care treatment for nonclear RCC. However, genetic analysis revealed a germline pathogenic variant of fumarate hydratase (FH) gene, and the patient had a sustained and durable response to pazopanib.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Durable Response to Pazopanib in a Patient with Fumarate Hydratase-Mutant Tubulocystic Renal Cell Carcinoma ; volume:16 ; number:1 ; year:2023 ; pages:240-248 ; extent:9
Case reports in oncology ; 16, Heft 1 (2023), 240-248 (gesamt 9)
- Urheber
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Othman, Anjum
Kumar, Shiyam
Qureshi, Asim
Jawa, Zabah M.
Burney, Ikram A.
- DOI
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10.1159/000528697
- URN
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urn:nbn:de:101:1-2023122723362388208103
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:36 MESZ
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Beteiligte
- Othman, Anjum
- Kumar, Shiyam
- Qureshi, Asim
- Jawa, Zabah M.
- Burney, Ikram A.
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