The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection

to related objects

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: 1 Online-Ressource.

Language: Englisch

Bibliographic citation: The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection ; volume:24 ; number:1 ; day:13 ; month:3 ; year:2023 ; pages:1-23 ; date:12.2023
Genome biology ; 24, Heft 1 (13.3.2023), 1-23, 12.2023

Creator: Goldswain, Hannah
Dong, Xiaofeng
Penrice-Randal, Rebekah
Alruwaili, Muhannad
Shawli, Ghada T.
Prince, Tessa
Williamson, Maia Kavanagh
Raghwani, Jayna
Randle, Nadine
Jones, Benjamin
Donovan-Banfield, I’ah
Salguero, Francisco J.
Tree, Julia A.
Hall, Yper
Hartley, Catherine
Erdmann, Maximilian
Bazire, James
Jearanaiwitayakul, Tuksin
Semple, Malcolm G.
Openshaw, Peter J. M.
Baillie, J. Kenneth
Emmett, Stevan R.
Digard, Paul
Matthews, David A.
Turtle, Lance
Darby, Alistair C.
Davidson, Andrew D.
Carroll, Miles W.
Hiscox, Julian A.

Contributor: SpringerLink (Online service)

DOI: 10.1186/s13059-023-02881-5

URN: urn:nbn:de:101:1-2408120906245.700335034820

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:45 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Goldswain, Hannah
Dong, Xiaofeng
Penrice-Randal, Rebekah
Alruwaili, Muhannad
Shawli, Ghada T.
Prince, Tessa
Williamson, Maia Kavanagh
Raghwani, Jayna
Randle, Nadine
Jones, Benjamin
Donovan-Banfield, I’ah
Salguero, Francisco J.
Tree, Julia A.
Hall, Yper
Hartley, Catherine
Erdmann, Maximilian
Bazire, James
Jearanaiwitayakul, Tuksin
Semple, Malcolm G.
Openshaw, Peter J. M.
Baillie, J. Kenneth
Emmett, Stevan R.
Digard, Paul
Matthews, David A.
Turtle, Lance
Darby, Alistair C.
Davidson, Andrew D.
Carroll, Miles W.
Hiscox, Julian A.
SpringerLink (Online service)

Other Objects (12)

Loss of T‐bet confers survival advantage to influenza–bacterial superinfection

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic

Arbeitspapier

Substitution and Complementarity under Comparative Advantage and the Accumulation of Human Capital

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Schnellnachweis von SARS-CoV-2 mit recombinase polymerase amplification

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Fourth NF-κB site in HIV-1 subtype-C LTR confers functional advantage to viral gene expression

Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

SARS-CoV-2 RNA polymerase as target for antiviral therapy

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

Loss of T‐bet confers survival advantage to influenza–bacterial superinfection

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic

Arbeitspapier

Substitution and Complementarity under Comparative Advantage and the Accumulation of Human Capital

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Schnellnachweis von SARS-CoV-2 mit recombinase polymerase amplification

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Fourth NF-κB site in HIV-1 subtype-C LTR confers functional advantage to viral gene expression

Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

SARS-CoV-2 RNA polymerase as target for antiviral therapy

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

Loss of T‐bet confers survival advantage to influenza–bacterial superinfection

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic

Arbeitspapier

Substitution and Complementarity under Comparative Advantage and the Accumulation of Human Capital

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Schnellnachweis von SARS-CoV-2 mit recombinase polymerase amplification

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Fourth NF-κB site in HIV-1 subtype-C LTR confers functional advantage to viral gene expression

Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

SARS-CoV-2 RNA polymerase as target for antiviral therapy

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read the terms of use and the privacy policy for the collection of personal data and accept them. *

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection

Object Details

References and Relationships

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

Loss of T‐bet confers survival advantage to influenza–bacterial superinfection

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic

Substitution and Complementarity under Comparative Advantage and the Accumulation of Human Capital

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Schnellnachweis von SARS-CoV-2 mit recombinase polymerase amplification

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Fourth NF-κB site in HIV-1 subtype-C LTR confers functional advantage to viral gene expression

Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

SARS-CoV-2 RNA polymerase as target for antiviral therapy

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

Loss of T‐bet confers survival advantage to influenza–bacterial superinfection

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic

Substitution and Complementarity under Comparative Advantage and the Accumulation of Human Capital

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Schnellnachweis von SARS-CoV-2 mit recombinase polymerase amplification

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Fourth NF-κB site in HIV-1 subtype-C LTR confers functional advantage to viral gene expression

Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

SARS-CoV-2 RNA polymerase as target for antiviral therapy

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

Loss of T‐bet confers survival advantage to influenza–bacterial superinfection

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic

Substitution and Complementarity under Comparative Advantage and the Accumulation of Human Capital

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Schnellnachweis von SARS-CoV-2 mit recombinase polymerase amplification

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Fourth NF-κB site in HIV-1 subtype-C LTR confers functional advantage to viral gene expression

Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

SARS-CoV-2 RNA polymerase as target for antiviral therapy

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

Related objects

Reset password