Acquired von Willebrand syndrome in patients with ventricular assist device

Abstract: During the last decade the use of ventricular assist devices (VADs) for patients with severe heart failure has increased tremendously. However, flow disturbances, mainly high shear induced by the device is associated with bleeding complications. Shear stress-induced changes in VWF conformation are associated with a loss of high molecular weight multimers (HMW) of VWF and an increased risk of bleeding. This phenomenon and its cause will be elaborated and reviewed in the following

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
issn: 2296-858X

Keyword
Willebrand-Jürgens-Syndrom
Willebrand-Faktor

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2019
Creator
Rauch, Antoine
Susen, Sophie
Zieger, Barbara

DOI
10.3389/fmed.2019.00007
URN
urn:nbn:de:bsz:25-freidok-1492192
Rights
Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:49 PM CET

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Associated

Time of origin

  • 2019

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