Sox9: A potential regulator of cancer stem cells in osteosarcoma
Abstract: Osteosarcoma is a highly aggressive bone tumor primarily affecting children and adolescents. Despite advancements in treatment modalities, the prognosis for osteosarcoma patients remains poor, emphasizing the need for a deeper understanding of its underlying mechanisms. In recent years, the concept of cancer stem cells (CSCs) has emerged as a crucial factor in tumor initiation, progression, and therapy resistance. These specialized subpopulations of cells possess self-renewal capacity, tumorigenic potential, and contribute to tumor heterogeneity. Sox9, a transcription factor known for its critical role in embryonic development and tissue homeostasis, has been implicated in various malignancies, including osteosarcoma. This review aims to summarize the current knowledge regarding the role of Sox9 in CSCs in osteosarcoma and its potential implications as a prognosis and therapeutic target.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Sox9: A potential regulator of cancer stem cells in osteosarcoma ; volume:19 ; number:1 ; year:2024 ; extent:9
Open medicine ; 19, Heft 1 (2024) (gesamt 9)
- Urheber
-
Li, Xiucheng
Lv, Zuo
Zhou, Ping
Zhang, SongOu
Jiang, Chao
- DOI
-
10.1515/med-2024-0995
- URN
-
urn:nbn:de:101:1-2407081550029.935359536257
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
- 14.08.2025, 10:56 MESZ
Datenpartner
Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Li, Xiucheng
- Lv, Zuo
- Zhou, Ping
- Zhang, SongOu
- Jiang, Chao
Ähnliche Objekte (12)
Nanotechnology as a field of science: Its delineation in terms of journals and patents
Identification of E2F transcription factor 7 as a novel potential biomarker for oral squamous cell carcinoma
The relationship between interdisciplinarity and citation impact—a novel perspective on citation accumulation
Toward attenuating the impact of arm positions on electromyography pattern-recognition based motion classification in transradial amputees
A projection continuation approach for minimal coordinate set constrained dynamics
Contribution of human hematopoietic stem cells to liver repair
Remote preparation for single-photon two-qubit hybrid state with hyperentanglement via linear-optical elements
RETRACTED ARTICLE: Meta-analysis of the efficacy of pancreatoduodenectomy with extended lymphadenectomy in the treatment of pancreatic cancer
Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen
The effects of notch filtering on electrically evoked myoelectric signals and associated motor unit index estimates
A practice of caution: spontaneous action potentials or artifactual spikes?
Propagation of desert moss Syntrichia caninervis in peat pellet: a method for rapidly obtaining large numbers of cloned gametophytes
Nanotechnology as a field of science: Its delineation in terms of journals and patents
Identification of E2F transcription factor 7 as a novel potential biomarker for oral squamous cell carcinoma
The relationship between interdisciplinarity and citation impact—a novel perspective on citation accumulation
Toward attenuating the impact of arm positions on electromyography pattern-recognition based motion classification in transradial amputees
A projection continuation approach for minimal coordinate set constrained dynamics
Contribution of human hematopoietic stem cells to liver repair
Remote preparation for single-photon two-qubit hybrid state with hyperentanglement via linear-optical elements
RETRACTED ARTICLE: Meta-analysis of the efficacy of pancreatoduodenectomy with extended lymphadenectomy in the treatment of pancreatic cancer
Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen
The effects of notch filtering on electrically evoked myoelectric signals and associated motor unit index estimates
A practice of caution: spontaneous action potentials or artifactual spikes?
Propagation of desert moss Syntrichia caninervis in peat pellet: a method for rapidly obtaining large numbers of cloned gametophytes
Nanotechnology as a field of science: Its delineation in terms of journals and patents
Identification of E2F transcription factor 7 as a novel potential biomarker for oral squamous cell carcinoma
The relationship between interdisciplinarity and citation impact—a novel perspective on citation accumulation
Toward attenuating the impact of arm positions on electromyography pattern-recognition based motion classification in transradial amputees
A projection continuation approach for minimal coordinate set constrained dynamics
Contribution of human hematopoietic stem cells to liver repair
Remote preparation for single-photon two-qubit hybrid state with hyperentanglement via linear-optical elements
RETRACTED ARTICLE: Meta-analysis of the efficacy of pancreatoduodenectomy with extended lymphadenectomy in the treatment of pancreatic cancer
Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen
The effects of notch filtering on electrically evoked myoelectric signals and associated motor unit index estimates
A practice of caution: spontaneous action potentials or artifactual spikes?