Microfluidic Nanoparticles for Drug Delivery

Abstract: Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades. Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability in precisely controlling NP properties. The recent success of mRNA vaccines using microfluidics represents a big milestone for microfluidic NPs for pharmaceutical applications, and its rapid scaling up demonstrates the feasibility of using microfluidics for industrial‐scale manufacturing. This article provides a critical review of recent progress in microfluidic NPs for drug delivery. First, the synthesis of organic NPs using microfluidics focusing on typical microfluidic methods and their applications in making popular and clinically relevant NPs, such as liposomes, lipid NPs, and polymer NPs, as well as their synthesis mechanisms are summarized. Then, the microfluidic synthesis of several representative inorganic NPs (e.g., silica, metal, metal oxide, and quantum dots), and hybrid NPs is discussed. Lastly, the applications of microfluidic NPs for various drug delivery applications are presented.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Microfluidic Nanoparticles for Drug Delivery ; day:09 ; month:04 ; year:2022 ; extent:33
Small ; (09.04.2022) (gesamt 33)

Urheber
Liu, Yun
Yang, Guangze
Hui, Yue
Ranaweera, Supun
Zhao, Chun‐Xia

DOI
10.1002/smll.202106580
URN
urn:nbn:de:101:1-2022041215170000599504
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:33 MESZ

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Beteiligte

  • Liu, Yun
  • Yang, Guangze
  • Hui, Yue
  • Ranaweera, Supun
  • Zhao, Chun‐Xia

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