Initial experience with the Solitaire X 3 mm stent retriever for the treatment of distal medium vessel occlusions

Abstract: Endovascular therapy (EVT) is the standard treatment for ischemic stroke caused by a large vessel occlusion (LVO). The effectiveness of EVT for distal medium vessel occlusions (MDVOs) is still uncertain, but newer, smaller devices show potential for EVT in MDVOs. The new Solitaire X 3 mm device offers a treatment option for MDVOs. Our study encompassed consecutive cases of primary and secondary MDVOs treated with the Solitaire X 3 mm stent-retriever as first-line EVT device between January and December 2022 at 12 European stroke centers. The primary endpoint was a first-pass near-complete or complete reperfusion, defined as a modified treatment in cerebral infarction (mTICI) score of 2c/3. Additionally, we examined reperfusion results, National Institutes of Health Stroke Scale (NIHSS) scores at 24 h and discharge, device malfunctions, complications and procedural technical parameters. Sixty-eight patients (38 women, mean age 72 ± 14 years) were included in our study. Median NIHSS at admission was 11 (IQR 6–16). In 53 (78%) cases, a primary combined approach was used as the frontline technique. Among all enrolled patients, first-pass mTICI 2c/3 was achieved in 22 (32%) and final mTICI 2c/3 in 46 (67.6%) patients after a median of 1.5 (IQR 1–2) passes. Final reperfusion mTICI 2b/3 was observed in 89.7% of our cases. We observed no device malfunctions. Median NIHSS at discharge was 2 (IQR 0–4), and no symptomatic intracranial hemorrhages were reported. Based on our analysis, the utilization of the Solitaire X 3 mm device appears to be both effective and safe for performing EVT in cases of MDVO stroke

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• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch
• Notes: Journal of Clinical Medicine. - 12, 23 (2023) , 7289, ISSN: 2077-0383

Classification and Topics

• Classification: Medizin, Gesundheit

Contributors, Places and Time

• Event: Veröffentlichung
• (where): Freiburg
• (who): Universität
• (when): 2023
• Creator: Ntoulias, Nikos ; Brehm, Alex ; Tsogkas, Ioannis ; Jesser, Jessica ; Caragliano, Antonio Armando ; Demerath, Theo ; van Es, A. C. G. M. ; Gruber, Phillip ; Vega, Pedro ; Lüttich, Alex ; Nayak, Sanjeev ; Fandiño, Eduardo ; Ribo, Marc ; Rodriguez Paz, Carlos Manuel ; Möhlenbruch, Markus Alfred ; Tessitore, Agostino ; Remonda, Luca ; Murias, Eduardo ; Blackham, Kristine A. ; Psychogios, Marios-Nikos

Further information

• DOI: 10.3390/jcm12237289
• URN: urn:nbn:de:bsz:25-freidok-2423495
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.