Using 3D-bioprinted autologous minimally manipulated homologous adipose tissue for limb salvage in the treatment of diabetic foot ulcer
Reconstructive surgeons face challenges when considering limb salvage methods for the treatment of diabetic foot ulcers (DFUs). In this article, we present our experience with autologous fat grafting as a viable alternative in cases where flap reconstruction is difficult. We encountered a 78-year-old female patient with a non-healing DFU who had multiple comorbidities, including renal failure and severe peripheral arterial disease (PAD). During the initial multidisciplinary meeting, due to extensive necrosis and osteomyelitis, amputation was recommended. However, the patient expressed a strong preference for a salvage procedure and refused amputation. After careful consideration, we opted to reconstruct the patient's foot using 3D-bioprinted autologous minimally manipulated homologous adipose tissue (3D-AMHAT). The AMHAT was engrafted well without complications such as autolysis, graft failure or infection. After the operation, the large defect with partial bone exposure was covered with healthy granulation tissue. The size of the wound decreased to less than half its original size after 6 weeks of surgery, and it decreased to less than 25% after 12 weeks of surgery. The AMHAT may be an appealing treatment option for diabetic foot patients who are unsuitable for flap reconstruction due to comorbidities.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Using 3D-bioprinted autologous minimally manipulated homologous adipose tissue for limb salvage in the treatment of diabetic foot ulcer ; day:07 ; month:02 ; year:2024
Archives of Plastic Surgery ; (07.02.2024)
- Contributor
-
Yoon, Hyeonmin
Song, Woojin
- DOI
-
10.1055/a-2263-7957
- URN
-
urn:nbn:de:101:1-2024032811063836229198
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
- 14.08.2025, 10:46 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Yoon, Hyeonmin
- Song, Woojin
Other Objects (12)
Salvage
Salvage Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) for T4b Esophageal Cancer After Definitive Chemoradiotherapy
Use of autologous fascia lata graft to repair a complex corneal ulcer in a mare
Leg Ulcer Therapy by Local Injection of Autologous Growth Factors: Results of a Pilot Study
Over-the-scope clip as salvage therapy in refractory bleeding from esophageal variceal band ligation-induced ulcer
Transthoracic minimally invasive closure for the treatment of arch penetrating aortic ulcer: a case report
Homologous triangles.
Homologous triangles.
Duodenal ulcer
Limb salvage
Correction to: Leg Ulcer Therapy by Local Injection of Autologous Growth Factors: Results of a Pilot Study
La "Salvage Section"
Salvage
Salvage Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) for T4b Esophageal Cancer After Definitive Chemoradiotherapy
Use of autologous fascia lata graft to repair a complex corneal ulcer in a mare
Leg Ulcer Therapy by Local Injection of Autologous Growth Factors: Results of a Pilot Study
Over-the-scope clip as salvage therapy in refractory bleeding from esophageal variceal band ligation-induced ulcer
Transthoracic minimally invasive closure for the treatment of arch penetrating aortic ulcer: a case report
Homologous triangles.
Homologous triangles.
Duodenal ulcer
Limb salvage
Correction to: Leg Ulcer Therapy by Local Injection of Autologous Growth Factors: Results of a Pilot Study
La "Salvage Section"
Salvage
Salvage Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) for T4b Esophageal Cancer After Definitive Chemoradiotherapy
Use of autologous fascia lata graft to repair a complex corneal ulcer in a mare
Leg Ulcer Therapy by Local Injection of Autologous Growth Factors: Results of a Pilot Study
Over-the-scope clip as salvage therapy in refractory bleeding from esophageal variceal band ligation-induced ulcer
Transthoracic minimally invasive closure for the treatment of arch penetrating aortic ulcer: a case report
Homologous triangles.
Homologous triangles.
Duodenal ulcer
Limb salvage
Correction to: Leg Ulcer Therapy by Local Injection of Autologous Growth Factors: Results of a Pilot Study