Nanographenes: Ultrastable, Switchable, and Bright Probes for Super‐Resolution Microscopy
Abstract: Super‐resolution fluorescence microscopy has enabled important breakthroughs in biology and materials science. Implementations such as single‐molecule localization microscopy (SMLM) and minimal emission fluxes (MINFLUX) microscopy in the localization mode exploit fluorophores that blink, i.e., switch on and off, stochastically. Here, we introduce nanographenes, namely large polycyclic aromatic hydrocarbons that can also be regarded as atomically precise graphene quantum dots, as a new class of fluorophores for super‐resolution fluorescence microscopy. Nanographenes exhibit outstanding photophysical properties: intrinsic blinking even in air, excellent fluorescence recovery, and stability over several months. As a proof of concept for super‐resolution applications, we use nanographenes in SMLM to generate 3D super‐resolution images of silica nanocracks. Our findings open the door for the widespread application of nanographenes in super‐resolution fluorescence microscopy.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Nanographenes: Ultrastable, Switchable, and Bright Probes for Super‐Resolution Microscopy ; volume:59 ; number:1 ; year:2020 ; pages:496-502 ; extent:7
Angewandte Chemie / International edition. International edition ; 59, Heft 1 (2020), 496-502 (gesamt 7)
- Creator
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Liu, Xiaomin
Chen, Shih‐Ya
Chen, Qiang
Yao, Xuelin
Gelléri, Márton
Ritz, Sandra
Kumar, Sachin
Cremer, Christoph
Landfester, Katharina
Müllen, Klaus
Parekh, Sapun H.
Narita, Akimitsu
Bonn, Mischa
- DOI
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10.1002/anie.201909220
- URN
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urn:nbn:de:101:1-2022052707183476741026
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
- 27.12.0007, 3:30 PM CET
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Liu, Xiaomin
- Chen, Shih‐Ya
- Chen, Qiang
- Yao, Xuelin
- Gelléri, Márton
- Ritz, Sandra
- Kumar, Sachin
- Cremer, Christoph
- Landfester, Katharina
- Müllen, Klaus
- Parekh, Sapun H.
- Narita, Akimitsu
- Bonn, Mischa
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