Supercritical Fluid Chromatography in Bioanalysis–A Review

Abstract: In the last decade, the instrumentation improvements in supercritical fluid chromatography (SFC) and the hyphenation to mass spectrometry (MS), have increased the SFC acceptance between scientists, becoming today a valuable tool in analytical chemistry. The unique selectivity, short analysis times, low consumption of organic solvents, and the greener mobile phase, have contributed to expanding its applicability which has led to an increase in the number of publications especially in the bioanalysis area. This work reviews the advantages and main applications of SFC in bioanalysis during the last 5 years. Fundamental aspects concerning mobile phase composition, stationary phase, hyphenation to MS as well as matrix effect have been discussed. Finally, the most relevant applications have been summarized.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Supercritical Fluid Chromatography in Bioanalysis–A Review ; volume:47 ; number:21 ; year:2024 ; extent:19
Journal of separation science ; 47, Heft 21 (2024) (gesamt 19)

Urheber
Toribio, Laura
Martín, María Teresa
Bernal, José

DOI
10.1002/jssc.70003
URN
urn:nbn:de:101:1-2411021338081.830628721007
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 05:27 UTC

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Beteiligte

  • Toribio, Laura
  • Martín, María Teresa
  • Bernal, José

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