Nipple-sparing Mastectomy with Immediate Implant-based Reconstruction for Patients with Pure Ductal Carcinoma in Situ

Abstract: Objective The presence of an extensive intraductal component is associated to an increasing risk of relapse in the nipple-areola complex. The aim of the present study was to evaluate the outcomes of patients diagnosed with ductal carcinoma in situ (DCIS) who underwent nipple-sparing mastectomy (NSM) with immediate breast reconstruction using silicone implants. Methods We retrospectively analyzed the postoperative complications and oncological safety of 67 breast cancer patients diagnosed with pure DCIS who underwent NSM with immediate breast reconstruction using silicone implants between 2004 and 2018. Results Among the 127 NSM procedures performed, 2 hematomas (1.5%) and 1 partial nipple necrosis (0.7%) were observed. After a mean follow-up of 60 months, the local recurrence rate was of 8.9%, the disease-free survival rate was of 90%, and 1 of the patients died. Conclusion Despite the local recurrence rate, we showed that NSM with immediate breast reconstruction using silicone implants is a feasible surgical approach, with a low rate of complications and high survival rates for patients with a diagnosis of pure DCIS when breast-conserving surgery is not an option.

Weitere Titel
Mastectomia preservadora de mamilo com reconstrução imediata baseada em implante para pacientes com carcinoma ductal puro in situ
Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Nipple-sparing Mastectomy with Immediate Implant-based Reconstruction for Patients with Pure Ductal Carcinoma in Situ ; volume:44 ; number:04 ; year:2022 ; pages:376-384
Revista brasileira de ginecologia e obstetrícia ; 44, Heft 04 (2022), 376-384

Beteiligte Personen und Organisationen
Frasson, Antônio Luiz
Falcone, Ana Beatriz
Miranda, Isabela
Souza, Alessandra Borba Anton de
Vollbrecht, Betina
Barbosa, Fernanda
Frasson, Mônica Adriana Rodriguez Martinez
Lichtenfels, Martina

DOI
10.1055/s-0042-1742315
URN
urn:nbn:de:101:1-2022100814431293709004
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:22 MESZ

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Beteiligte

  • Frasson, Antônio Luiz
  • Falcone, Ana Beatriz
  • Miranda, Isabela
  • Souza, Alessandra Borba Anton de
  • Vollbrecht, Betina
  • Barbosa, Fernanda
  • Frasson, Mônica Adriana Rodriguez Martinez
  • Lichtenfels, Martina

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