Research progress on the mechanism of orexin in pain regulation in different brain regions
Abstract: Orexin is a neuropeptide that is primarily synthesized and secreted by the lateral hypothalamus (LH) and includes two substances derived from the same precursor (orexin A [OXA] and orexin B [OXB]). Studies have shown that orexin is not only involved in the regulation of eating, the sleep–wake cycle, and energy metabolism, but also closely associated with various physiological functions, such as cardiovascular control, reproduction, stress, reward, addiction, and the modulation of pain transmission. At present, studies that have been performed both domestically and abroad have confirmed that orexin and its receptors are closely associated with pain regulation. In this article, the research progress on acute pain regulation involving orexin is reviewed.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Research progress on the mechanism of orexin in pain regulation in different brain regions ; volume:16 ; number:1 ; year:2021 ; pages:46-52 ; extent:7
Open life sciences ; 16, Heft 1 (2021), 46-52 (gesamt 7)
- Urheber
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Kang, Xianhui
Tang, Hongli
Liu, Yao
Yuan, Yan
Wang, Mi
- DOI
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10.1515/biol-2021-0001
- URN
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urn:nbn:de:101:1-2022091914592673393978
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:24 MESZ
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Beteiligte
- Kang, Xianhui
- Tang, Hongli
- Liu, Yao
- Yuan, Yan
- Wang, Mi
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