Stereoselective Construction of Tertiary Homoallyl Alcohols and Ethers by Nucleophilic Substitution at Quaternary Carbon Stereocenters
Abstract: An efficient method for the stereoselective construction of tertiary C−O bonds via a stereoinvertive nucleophilic substitution at the quaternary carbon stereocenter of cyclopropyl carbinol derivatives using water, alcohols and phenols as nucleophiles has been developed. This substitution reaction proceeds under mild conditions and tolerates several functional groups, providing a new access to the stereoselective formation of highly congested tertiary homoallyl alcohols and ethers.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Stereoselective Construction of Tertiary Homoallyl Alcohols and Ethers by Nucleophilic Substitution at Quaternary Carbon Stereocenters ; day:13 ; month:12 ; year:2022 ; extent:1
Angewandte Chemie / International edition. International edition ; (13.12.2022) (gesamt 1)
- Creator
- DOI
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10.1002/anie.202212425
- URN
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urn:nbn:de:101:1-2022121414035005668010
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:26 AM CEST
Data provider
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Associated
- Chen, Xu
- Patel, Kaushalendra
- Marek, Ilan
Other Objects (12)
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Stereoselective Construction of Tertiary Homoallyl Alcohols and Ethers by Nucleophilic Substitution at Quaternary Carbon Stereocenters
Stereoinvertive Nucleophilic Substitution at Quaternary Carbon Stereocenters of Cyclopropyl Ketones and Ethers
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UAV patrol path planning based on machine vision and multi-sensor fusion
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SPIN1, negatively regulated by miR-148/152, enhances Adriamycin resistance via upregulating drug metabolizing enzymes and transporter in breast cancer
Stereoselective Construction of Tertiary Homoallyl Alcohols and Ethers by Nucleophilic Substitution at Quaternary Carbon Stereocenters
Stereoinvertive Nucleophilic Substitution at Quaternary Carbon Stereocenters of Cyclopropyl Ketones and Ethers
Stereoinvertive Nucleophilic Substitution at Quaternary Carbon Stereocenters of Cyclopropyl Ketones and Ethers
UAV patrol path planning based on machine vision and multi-sensor fusion
Prognostic value of electrocorticography and surface EEG in epilepsy patients with unilateral hippocampal sclerosis undergoing selective amygdalohippocampectomy
Multilingual Analysis of Food Words
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Mean-field formulation for mean-variance asset-liability management with cash flow under an uncertain exit time
Dynamic regulation of plasmodesmatal permeability and its application to horticultural research