Type I interferon receptor signaling in astrocytes regulates hippocampal synaptic plasticity and cognitive function of the healthy CNS
Abstract: Interferon (IFN) signaling within the CNS is critical for synaptic plasticity and processes of learning and memory formation under physiological conditions. Hosseini et al. provide evidence that the type I IFN receptor (IFNAR) is mediating this effect via the glutamate-aspartate transporter (GLAST) in astrocytes by regulating synaptic glutamate levels
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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Cell reports. - 31, 7 (2020) , 107666, ISSN: 2211-1247
- Event
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Veröffentlichung
- (where)
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Freiburg
- (who)
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Universität
- (when)
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2020
- Creator
- DOI
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10.1016/j.celrep.2020.107666
- URN
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urn:nbn:de:bsz:25-freidok-1659721
- Rights
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
- 14.08.2025, 10:52 AM CEST
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Associated
Time of origin
- 2020
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