Attention-deficit/hyperactivity disorder: the impact of methylphenidate on working memory, inhibition capacity and mental flexibility

Objective: To compare children with attention-deficit/hyperactivity disorder (ADHD), before and after the use of methylphenidate, and a control group, using tests of working memory, inhibition capacity and mental flexibility. Methods: Neuropsychological tests were administrated to 53 boys, 9–12 years old: the WISC-III digit span backward, and arithmetic; Stroop Color; and Trail Making Tests. The case group included 23 boys with ADHD, who were combined type, treatment-naive, and with normal intelligence without comorbidities. The control group (n = 30) were age and gender matched. After three months on methylphenidate, the ADHD children were retested. The control group was also retested after three months. Results: Before treatment, ADHD children had lower scores than the control group on the tests (p ≤ 0.001) and after methylphenidate had fewer test errors than before (p ≤ 0.001) Conclusion: Methylphenidate treatment improves the working memory, inhibitory control and mental flexibility of ADHD boys.

Weitere Titel
Transtorno do déficit de atenção/hiperatividade (TDAH): o impacto do metilfenidato na memória operacional, capacidade inibitória e flexibilidade mental
Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Attention-deficit/hyperactivity disorder: the impact of methylphenidate on working memory, inhibition capacity and mental flexibility ; volume:75 ; number:04 ; year:2017 ; pages:204-208
Arquivos de neuro-psiquiatria ; 75, Heft 04 (2017), 204-208

Beteiligte Personen und Organisationen
Bolfer, Cristiana
Pacheco, Sandra Pasquali
Tsunemi, Miriam Harumi
Carreira, Walter Souza
Casella, Beatriz Borba
Casella, Erasmo Barbante

DOI
10.1590/0004-282X20170030
URN
urn:nbn:de:101:1-2023101911195378690227
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 11:03 MESZ

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Beteiligte

  • Bolfer, Cristiana
  • Pacheco, Sandra Pasquali
  • Tsunemi, Miriam Harumi
  • Carreira, Walter Souza
  • Casella, Beatriz Borba
  • Casella, Erasmo Barbante

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