Neuropathology of COVID-19 (neuro-COVID): clinicopathological update

Abstract: Coronavirus disease 2019 (COVID-19) is emerging as the greatest public health crisis in the early 21st century. Its causative agent, Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), is an enveloped single-stranded positive-sense ribonucleic acid virus that enters cells via the angiotensin converting enzyme 2 receptor or several other receptors. While COVID-19 primarily affects the respiratory system, other organs including the brain can be involved. In Western clinical studies, relatively mild neurological dysfunction such as anosmia and dysgeusia is frequent (~70-84%) while severe neurologic disorders such as stroke (~1-6%) and meningoencephalitis are less common. It is unclear how much SARS-CoV-2 infection contributes to the incidence of stroke given co-morbidities in the affected patient population. Rarely, clinically-defined cases of acute disseminated encephalomyelitis, Guillain-Barré syndrome and acute necrotizing encephalopathy have been reported in COVID-19 p.... https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/2993

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Neuropathology of COVID-19 (neuro-COVID): clinicopathological update ; volume:2 ; day:18 ; month:01 ; year:2021 ; Free Neuropathology ; 2 (18.01.2021)

Contributors, Places and Time

• Creator: Lou, Jerry J. ; Movassaghi, Mehrnaz ; Gordy, Dominique ; Olson, Madeline G. ; Zhang, Ting ; Khurana, Maya S. ; Chen, Zesheng ; Perez-Rosendahl, Mari ; Thammachantha, Samasuk ; Singer, Elyse J. ; Magaki, Shino D. ; Vinters, Harry V. ; Yong, William H.

Further information

• URN: urn:nbn:de:hbz:6:3-freeneuropathology-2021-31738
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:48 AM CEST